Super-Resolution Nanothermometry on Live Cells

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This project aims to deliver new temperature sensors and advance the field of nanothermometry beyond its optical diffraction limit and current reliability issues. The project expects to forge a new way to study organelle metabolism and functional interactions by creating a super-resolution heat map of living cells. Expected outcomes include new knowledge of ionic energy transfer among lanthanide ions, innovative super-resolution imaging nanothermometers, new biochemistry and cell biology protocols, and spectroscopy and microscopy instruments. The adoption of these outcomes in new technologies should provide significant benefits in cell biology research, life sciences, engineering sciences and Australia’s imaging and sensor industries.