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Harnessing tissue-specific expression of E3 ligases for selective protein degradation in cancer

Harnessing tissue-specific expression of E3 ligases for selective protein degradation in cancer
利用 E3 连接酶的组织特异性表达来选择性降解癌症中的蛋白质
批准号:
455096
负责人:
Barghout Samir
金额:
$9.83万
依托单位:
依托单位国家:
加拿大
项目类别:
Fellowship Programs
财政年份:
2021
资助国家:
加拿大
项目状态:
已结题
起止时间:
2021-10-01 至 2024-10-01

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英文摘要
The existing arsenal of cancer therapies comprises drugs that act mostly by modifying the function of their targets with little or no impact on their protein levels. A novel approach known as targeted protein degradation has recently emerged whereby drugs
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