CRUI: Phenotypic Plasticity in Reproduction: Molecular Mechanisms, Physiological Control, and Adaptive Significance

CRUI：生殖中的表型可塑性：分子机制、生理控制和适应性意义

• 批准号: 9510979
• 负责人: Steven Juliano
• 金额: $ 92.48万
• 依托单位: Board of Trustees of Illinois State University
• 依托单位国家: 美国
• 项目类别: Continuing Grant
• 财政年份: 1995
• 资助国家: 美国
• 起止时间: 1995-09-15 至 2000-01-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=9510979&HistoricalAwards=false
• 关键词: CRUI; Phenotypic; Plasticity; Reproduction; Molecular

This project is for Collaborative Research at Undergraduate Institutions, involving molecular biology, physiology and ecology to understand how reproduction is affected by environmental stresses. It is well known from ecological and evolutionary research that organisms have considerable flexibility in how they respond to variable and unpredictable environments, and physiological and cellular mechanisms such as endocrine function have been well studied. However, the means by which the environmental stimuli mediate their effects through physiological and molecular mechanisms are not well understood. This project uses laboratory and field experiments on a large insect as a model system to determine how variations in temperature and food availability affect the cellular, molecular and physiological events that accompany egg production, egg laying, and the development and survival of offspring. Manipulations of these variables will indicate whether this reproductive plasticity represents an adaptive response or an environmental constraint. Results will have an impact on developmental biology, ecology, evolutionary biology, insect biology and pest control, and promises a novel integrative experience involving undergraduates in exciting research over an unusual range of levels of biological organization.

这个项目是在本科院校的合作研究，涉及分子生物学，生理学和生态学，以了解生殖是如何受到环境压力。 从生态学和进化研究中众所周知，生物体在如何应对可变和不可预测的环境方面具有相当大的灵活性，并且已经对内分泌功能等生理和细胞机制进行了充分研究。 然而，环境刺激通过生理和分子机制介导其效应的手段还不清楚。 该项目使用大型昆虫作为模型系统的实验室和田间实验，以确定温度和食物供应的变化如何影响伴随产卵，产卵以及后代发育和生存的细胞，分子和生理事件。 对这些变量的操纵将表明这种生殖可塑性是一种适应性反应还是一种环境约束。 结果将对发育生物学，生态学，进化生物学，昆虫生物学和害虫控制产生影响，并承诺一种新颖的综合体验，涉及本科生在生物组织水平的不寻常范围内进行令人兴奋的研究。