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Characterizing roles of the WAVE2 actin-regulatory protein in immune homeostasis and autoimmunity

Characterizing roles of the WAVE2 actin-regulatory protein in immune homeostasis and autoimmunity
WAVE2 肌动蛋白调节蛋白在免疫稳态和自身免疫中的作用特征
批准号:
470144
负责人:
Siminovitch Katherine A
金额:
$75.24万
依托单位国家:
加拿大
项目类别:
Operating Grants
财政年份:
2022
资助国家:
加拿大
项目状态:
未结题
起止时间:
2022-09-01 至 2027-09-01

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中文摘要
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英文摘要
The immune system plays a critical role in human health as evidenced by the wide range of diseases caused by impaired immunity. One group of proteins which play essential roles in supporting immune cell function are the "actin cytoskeletal regulators". Th
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Resilience to age-related dementia by the microglial ABI-WAVE2 signaling axis
Characterizing molecular determinants of autoimmune disease
  • 批准号:
    333583
  • 项目类别:
    Operating Grants
  • 资助金额:
    $316.62万
  • 财政年份:
    2015
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    Siminovitch Katherine A
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CanDu COER - A Canadian-Dutch COnsortium for Ending Rheumatoid arthritis
  • 批准号:
    341243
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    Operating Grants
  • 资助金额:
    $1.46万
  • 财政年份:
    2015
  • 负责人:
    Siminovitch Katherine A
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Characterization of genetic/molecular pathways underpinning rheumatoid arthritis
  • 批准号:
    291452
  • 项目类别:
    Operating Grants
  • 资助金额:
    $40.63万
  • 财政年份:
    2013
  • 负责人:
    Siminovitch Katherine A
  • 依托单位:
海外基金