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Resilience to age-related dementia by the microglial ABI-WAVE2 signaling axis

Resilience to age-related dementia by the microglial ABI-WAVE2 signaling axis
小胶质细胞 ABI-WAVE2 信号轴对年龄相关性痴呆的抵抗力
批准号:
486745
负责人:
Siminovitch Katherine A
金额:
$54.64万
依托单位国家:
加拿大
项目类别:
Operating Grants
财政年份:
2023
资助国家:
加拿大
项目状态:
未结题
起止时间:
2023-07-01 至 2026-07-01
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中文摘要
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英文摘要
This research proposal aims to deliver new understanding of the fundamental cellular processes that modulate risk for and progression of cognitive impairment and dementia in aging. The research program is based on discoveries by this investigator team and
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Characterizing roles of the WAVE2 actin-regulatory protein in immune homeostasis and autoimmunity
Characterizing molecular determinants of autoimmune disease
  • 批准号:
    333583
  • 项目类别:
    Operating Grants
  • 资助金额:
    $316.62万
  • 财政年份:
    2015
  • 负责人:
    Siminovitch Katherine A
  • 依托单位:
CanDu COER - A Canadian-Dutch COnsortium for Ending Rheumatoid arthritis
  • 批准号:
    341243
  • 项目类别:
    Operating Grants
  • 资助金额:
    $1.46万
  • 财政年份:
    2015
  • 负责人:
    Siminovitch Katherine A
  • 依托单位:
Characterization of genetic/molecular pathways underpinning rheumatoid arthritis
  • 批准号:
    291452
  • 项目类别:
    Operating Grants
  • 资助金额:
    $40.63万
  • 财政年份:
    2013
  • 负责人:
    Siminovitch Katherine A
  • 依托单位:
海外基金