Molecular and Biochemical Analysis of a Plant K+ Channel beta Subunit

植物 K 通道 β 亚基的分子和生化分析

• 批准号: 9513921
• 负责人: Gerald Berkowitz
• 金额: $ 29.08万
• 依托单位: University of Connecticut
• 依托单位国家: 美国
• 项目类别: Continuing Grant
• 财政年份: 1996
• 资助国家: 美国
• 起止时间: 1996-09-01 至 2001-08-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=9513921&HistoricalAwards=false
• 关键词: Molecular; Biochemical; Analysis; Plant; K+

9513921 Berkowitz This research is to characterize a putative beta subunit of a plant K + channel. This molecule is a translation product of a cDNA from Arabidopsis which is 50% homologous to a recently characterized beta subunit in brain, which rapidly inactivates K channels by occluding the ion conduction path in the pore region of the protein. The research in this grant will be aimed at characterizing this channel and studying its interaction with the known K channels in plant cells. Since K+ channels are important to a number of processes in plant cells, information on their regulation is important. ***

小行星9513921 本研究旨在鉴定一种植物钾离子通道的β亚基。 该分子是来自拟南芥的cDNA的翻译产物，其与最近表征的脑中的β亚基具有50%同源性，其通过阻塞蛋白质的孔区域中的离子传导路径来快速失活K通道。 这项研究的目的是表征这种通道，并研究它与植物细胞中已知的K通道的相互作用。 由于K+通道对植物细胞中的许多过程都很重要，因此有关其调节的信息很重要。 ***