Molecular and Biochemical Analysis of a Plant K+ Channel beta Subunit

本研究的目的是表征植物K +通道的β亚基。该分子是拟南芥cDNA的翻译产物，其与最近发现的脑β亚基有50%的同源性，该亚基通过阻断蛋白质孔区的离子传导途径迅速失活K通道。这项资助的研究将旨在表征该通道并研究其与植物细胞中已知的K通道的相互作用。由于K+通道对植物细胞中的许多过程都很重要，因此有关其调控的信息很重要。＊＊＊

9513921 Berkowitz This research is to characterize a putative beta subunit of a plant K + channel. This molecule is a translation product of a cDNA from Arabidopsis which is 50% homologous to a recently characterized beta subunit in brain, which rapidly inactivates K channels by occluding the ion conduction path in the pore region of the protein. The research in this grant will be aimed at characterizing this channel and studying its interaction with the known K channels in plant cells. Since K+ channels are important to a number of processes in plant cells, information on their regulation is important. ***