SBIR PHASE I: The Development of a 600 MHz Wide Bore (89mm) High Resolution NMR Magnet with Internal Tin Wires

* 9561581吴 这个小企业创新研究第一阶段项目是研究开发600 MHz宽孔（89 mm）高分辨率NMR磁体的可行性，该磁体具有内部锡超导导线。 用内部锡丝代替铜丝，可大大降低高场核磁共振系统的成本。 第一阶段的研究目标是解决与内部锡线的高场NMR磁体的构造相关的工程问题。 为了实现这些目标，Cryomagnetics，Inc.将开发模型线圈，以实验方式确定持续模式操作中的内部锡丝稳定性。 第一阶段研究将包括NbTi和Nb3Sn接头的制造、线圈中应力分布的分析、退火工艺的优化、失超保护电路的设计以及持久模式下内部锡线圈稳定性的评估。 在第一阶段结束时，一个全尺寸的600兆赫宽孔核磁共振磁铁的工程设计将完成，这一设计将是第二阶段研究的起点，这将是针对一个全尺寸的核磁共振磁铁与内部锡线的发展。 第一阶段的预期结果是证明内部锡线在持续模式操作中的稳定性，并将内部锡线应用于高场NMR磁体。 第一阶段开发的新技术将通过降低NMR系统成本产生巨大的商业机会。 所提出的宽口径NMR磁体系统将是微成像和体内光谱以及生物固态NMR光谱的理想选择。 该项目一期和二期的顺利完成将使市场上出现低价格、宽口径、高场核磁共振磁体。 ***

*** 9561581 Wu This Small Business Innovation Research Phase I project is to study the feasibility of the development of a 600MHz wide bore (89mm) high resolution NMR magnet with internal tin superconducting wires. Replacing bronze-processed wire by internal tin wire, high field NMR system cost will be reduced significantly. The Phase I research objective is to solve engineering problems related to construction of high field NMR magnets with internal tin wire. To achieve the objectives, Cryomagnetics, Inc. will develop model coils to experimentally determine the internal tin wire stability in persistent mode operation. Phase I research will include fabrication of NbTi and Nb3Sn joints, analysis of stress distribution in the coils, optimization of the annealing process, design of quench protection circuits and evaluation of internal tin coil stability in persistent mode. At the end of Phase I, an engineering design of a full scale 600 MHz wide bore NMR magnet will be completed, and this design will be the starting point for Phase II research which will be directed toward development of a full scale NMR magnet with internal tin wire. The anticipated results from Phase I are to demonstrate the stability of internal tin wire in persistent mode operation and apply internal tin wire to high field NMR magnets. The new technologies developed in Phase I will generate great commercial opportunities by reducing NMR system costs. The proposed wide bore NMR magnet systems will be ideal for micro imaging and in vivo spectroscopy as well as biological solid state NMR spectroscopy. The successful completion of Phase I & II of this project will make low price, wide bore, high field NMR magnets available in the market. ***