U.S.-France Cooperative Research: Exotoxins as Tools in Delineating the Role of Rab5 in Endocytosis

*9603091斯塔尔这个为期两年的美法细胞生物学合作研究奖由华盛顿大学的菲利普·斯塔尔和蒙彼利埃二世大学的米歇尔·维达尔获得。该奖项为斯塔尔博士和一名博士后研究员提供旅行支持和生活费。本研究的目的是探讨低分子GTP酶Rab5调节内吞和吞噬作用的机制。这些过程是细胞结合和内化营养物质、生物活性多肽和毒素、物质和颗粒的过程。美国研究人员为这项合作带来了在体外内噬菌体融合方面的专业知识。法国研究人员在外毒素方面的经验补充了这一点。***

*** 9603091 Stahl This two-year award for U.S.-France cooperative research in cellular biology involves Phillip Stahl at Washington University and Michel Vidal at the University of Montpellier II. The award provides travel support and living expenses to Dr. Stahl and a postdoctoral researcher. The objective of the research is to investigate the mechanism by which rab5, a low molecular weight GTPase (enzyme) regulates endocytosis and phagocytosis. These are processes by which cells bind and internalize nutrients, biologically active peptides and toxins, substances and particles. The U.S. investigators bring to this collaboration expertise in in vitro endosome and phagosome fusion. This is complemented by the French investigator's experience with exotoxins. ***