Application of genomics to dissect Polycomb-group protein mediated control of plant development (PcG-code)

应用基因组学剖析多梳蛋白介导的植物发育控制（PcG 代码）

• 批准号: 105000844
• 负责人: Professor Dr. Heiko Schoof
• 金额: --
• 依托单位: Abteilung Pflanzenkrankheiten und Pflanzenschutz
• 依托单位国家: 德国
• 项目类别: Research Grants
• 财政年份: 2009
• 资助国家: 德国
• 起止时间: 2008-12-31 至 2012-12-31
• 项目状态: 已结题
• 来源: https://gepris.dfg.de/gepris/projekt/105000844?language=en
• 关键词: Application; genomics; dissect; Polycomb; group

The ERA-NET PcG-code aims to achieve three interdependent objectives. First, based on knowledge provided by existing genomic datasets new genes will be discovered that play an important role in plant development. Second, the existing genomic datasets will be complemented in order to unravel Polycomb Group Protein complexity in plants. Last, the knowledge gap between chromatin control of transcription factor networks and downstream target genes will be closed in a case study of root development. The aim is to identify “realizator genes” that translate the developmental impact driven by Polycomb Group-controlled transcription factor networks to cellular function.

ERA-NET PcG代码旨在实现三个相互依存的目标。首先，基于现有基因组数据集提供的知识，将发现在植物发育中发挥重要作用的新基因。其次，现有的基因组数据集将得到补充，以解开植物中Polycomb Group蛋白质的复杂性。最后，在根发育的案例研究中，染色质控制的转录因子网络和下游靶基因之间的知识差距将被关闭。目的是确定“实现基因”，这些基因将Polycomb Group控制的转录因子网络驱动的发育影响转化为细胞功能。