Genetic Structure of a Primate Hybrid Zone

灵长类杂交区的遗传结构

• 批准号: 9615150
• 负责人: Clifford Jolly
• 金额: $ 40.57万
• 依托单位: New York University
• 依托单位国家: 美国
• 项目类别: Continuing Grant
• 财政年份: 1997
• 资助国家: 美国
• 起止时间: 1997-03-15 至 2002-09-30
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=9615150&HistoricalAwards=false
• 关键词: Genetic; Structure; Primate; Hybrid; Zone

Jolly/Disotell/Phillips-Conroy When two natural populations interbreed, they tend to become genetically homogenized. If, however, individuals of mixed ancestry are relatively unfit, a narrow, intervening hybrid zone may persist for generations, filtering gene-flow between the populations. Many such hybrid zones are known, but few involve primates, even though hybridization was probably important in human prehistory. Our study brings together investigators at New York University, Washington University in St. Louis, and Addis Ababa University, Ethiopia. It combines powerful, new techniques of genetic analysis with field observation to investigate hybridization between two baboon populations, strikingly different in both behavior and appearance, whose ranges meet in Ethiopia. We have already collected and stored DNA from about a thousand baboons, of four generations. In three more field seasons we shall complete this dataset, and clarify ecological influences on hybridization by mapping the hybrid zone more widely. Each animal will be typed for hypervariable DNA markers. Their distribution will show how social behavior affects the genetic structure of the populations, reveal patterns of inter-group migration, and indicate the darwinian fitness of cross-breeders and their offspring. The result will be a unique picture of the dynamics of natural hybridization and the genetics of evolutionary divergence.

乔利/迪索特尔/菲利普斯-康罗伊当两个自然种群进行杂交时，他们往往会变得基因同质化。然而，如果混合血统的个体相对不适合，一个狭窄的、介于两者之间的杂交区域可能会持续几代人，过滤种群之间的基因流动。许多这样的杂交区域是已知的，但很少涉及灵长类动物，尽管杂交可能在人类史前时期很重要。我们的研究汇集了纽约大学、圣路易斯华盛顿大学和埃塞俄比亚亚的斯亚贝巴大学的研究人员。它将强大的基因分析新技术与野外观察相结合，研究两个在行为和外表上都截然不同的狒狒种群之间的杂交，这两个种群的范围在埃塞俄比亚相遇。我们已经收集并存储了大约1000只狒狒的DNA，它们来自四代。再过三个野外季节，我们将完成这个数据集，并通过更广泛地绘制杂交区域图来阐明生态对杂交的影响。每只动物都将被分型，以确定是否存在高变量DNA标记。它们的分布将显示社会行为如何影响种群的遗传结构，揭示群体间迁移的模式，并表明杂交育种者及其后代的达尔文适合度。其结果将是一幅关于自然杂交动态和进化分化遗传学的独特图景。