Mechanisms of Alkene-Metal Oxide Interactions

烯烃-金属氧化物相互作用的机制

• 批准号: 9619296
• 负责人: Kevin Gable
• 金额: $ 29万
• 依托单位: Oregon State University
• 依托单位国家: 美国
• 项目类别: Continuing Grant
• 财政年份: 1997
• 资助国家: 美国
• 起止时间: 1997-02-01 至 2000-06-30
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=9619296&HistoricalAwards=false
• 关键词: Mechanisms; Alkene; Metal; Oxide; Interactions

The focus of this research will involve the preparation of new rhenium compounds with the metallaoxetane motif. Compounds of the type LReOn will be the primary synthetic targets and these intermediates will be used to form rhenaoxetanes. The latter will serve as probes for the understanding of the mechanism of the epoxidation and the bishydroxylation of alkenes. A separate investigation of the chemistry of the reactive molecule Cp*ReO2 will also be undertaken. This molecule abstracts oxygen from epoxides and the mechanism of the process may be related to that for diolate cycloreversion. With this award, the Organic Dynamic Program is supporting the research of Dr. Kevin P. Gable of the Department of Chemistry at Oregon State University. Professor Gable will focus his work on developing a detailed understanding of how carbon-oxygen bonds are formed during the oxidation of alkenes mediated by transition metal oxides. Oxidations of this type form an important class of reactions for the preparation of commodity chemicals and the synthesis of fine chemicals.

这项研究的重点将涉及制备新的 具有金属氧杂环丁烷基序的化合物。 LReOn型化合物 将是主要的合成目标，这些中间体将是 用于形成双氧杂环丁烷。 后者将作为探测器， 了解环氧化反应的机理， 烯烃的双羟基化。 单独调查 反应性分子Cp* ReO 2的研究也将进行。 这种分子 从环氧化物中提取氧，该过程的机理可能是 与二醇盐环化逆转相关。 有了这个奖项，有机 动态计划正在支持Kevin P. Gable博士的研究。 俄勒冈州州立大学化学系。盖博教授会 他的工作重点是详细了解 在烯烃介导的氧化过程中形成碳-氧键 过渡金属氧化物。 这种类型的氧化形成了一种重要的 用于制备商品化学品的一类反应， 精细化学品的合成