Morphological Study of Aqueous Processing of Biopolymers

生物聚合物水处理的形态研究

• 批准号: 9624306
• 负责人: Samuel Gido
• 金额: $ 32.5万
• 依托单位: University of Massachusetts Amherst
• 依托单位国家: 美国
• 项目类别: Continuing Grant
• 财政年份: 1996
• 资助国家: 美国
• 起止时间: 1996-06-15 至 2001-05-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=9624306&HistoricalAwards=false
• 关键词: Morphological; Study; Aqueous; Processing; Biopolymers

9624306 Gido An integrated career development plan is proposed which includes strong components in both research and education. The major components of this plan are: (1) to build a research group of graduate students; (2) to assemble laboratory facilities and equipment; (3) to develop a nationally and internationally recognized research program; (4) to develop educational programs in graduate research training as well as class work for graduate and undergraduate students. The research component of this career development plan is interdisciplinary in the sense that the system of study is natural or biological in origin, but the aspects of this system that are of primary interest fall into the realm of polymer science and materials science. It is proposed to investigate natural silk spinning processes in silk worms and spiders so that these incredibly efficient processes may to be used as models for aqueous processing of genetically engineered biopolymers. The techniques employed in this research will be mainly electron microscopy, electron diffraction, energy dispersive X-ray spectroscopy (EDS), and electron energy loss image filtering (Gatan Imaging Filter) on cryogenically prepared samples. Using these techniques, structure will be corrolated with protein concentration in the aqueous silk solution and the concentration of various salts which are naturally present in the silk gland, and are thought to influence chain conformation and phase behavior. %%% The educational component of this CAREER grant involves outreach to high-school students and teachers, summer programs, and field trips. Results from this research will be incorporated into classroom teaching in order to illustrate general principles of polymer morphology, crystallography, electron microscopy, etc. The techniques discussed in classes are general techniques of polymer science and materials science. ***

9624306吉多一个综合的职业发展计划提出，其中包括在研究和教育的强大组件。 该计划的主要组成部分是：（1）建立一个研究生研究小组;（2）组装实验室设施和设备;（3）制定一个国内和国际公认的研究计划;（4）制定研究生研究培训教育计划以及研究生和本科生的课堂作业。 该职业发展计划的研究部分是跨学科的，因为研究系统是自然或生物起源的，但该系统的主要兴趣方面属于聚合物科学和材料科学领域。 建议研究蠕虫和蜘蛛的天然丝纺丝过程，以便这些令人难以置信的高效过程可以用作基因工程生物聚合物的水处理的模型。 在这项研究中采用的技术将主要是电子显微镜，电子衍射，能量色散X射线光谱（EDS），和电子能量损失图像过滤（Gatan成像过滤器）对低温制备的样品。 使用这些技术，结构将与丝水溶液中的蛋白质浓度和天然存在于丝腺中的各种盐的浓度相关联，并且被认为影响链构象和相行为。 %此职业生涯补助金的教育部分涉及到高中学生和教师，暑期课程和实地考察。 从这项研究的结果将被纳入课堂教学，以说明聚合物形态学，晶体学，电子显微镜等的一般原则，在课堂上讨论的技术是聚合物科学和材料科学的一般技术。 ***