New Versatile and Stable Artificial Enzymes

在有机动力学项目的资助下，休斯顿大学的李教授将研究制备人造酶的新的、通用的方法。这项研究将集中在使用烷硫基单元将环糊精部分单层结合到金表面上。此外，在环糊精腔内，应将额外的烷硫基连接到金表面，并用于定位反应物以增强催化活性。在调查的教育部分，首席调查员将邀请几位来自当地行业的讲师在一个新的课程“过程化学和石油化学的环境方面”中讲授，以促进学生对工业环境的了解。此外，还将增加一门课程，主题为《上下文中的化学》。控制反应的拓扑结构以促进预期的反应是许多科学家的主要目标。有机动力学项目的这一奖项通过将人工催化单元系在黄金表面并使用烷硫醇单元来调整内部催化环境来解决这一主题。该奖项的教育部分将通过引入两门新课程，为本科生和研究生的研究生职业生涯做好准备。第一门课将教他们化学是如何融入日常生活的，题目是《上下文中的化学》。在第二个课程中，工业科学家将被邀请讲授几场关于工业职业的讲座和观点。

With funding from the Organic Dynamics Program, Professor Lee of the University of Houston will investigate new and versatile approaches to the preparation of artificial enzymes. The research will focus on the use of alkanethio units to bind a monolayer of cyclodextrin moieties to a gold surface. Further, within the cyclodextrin cavity, additional alkanethio units shall be bonded to the gold surface and used to position the reactants for enhanced catalytic activity. For the education portion of the investigation, the principal investigator will facilitate student understanding of the industrial environment by inviting several lecturers from the local industries to talk in a new course on `Process Chemistry and Environmental Aspects of Petrochemistry`. In addition, a second course will be added on the subject `Chemistry in Context`. Control of reaction topology to facilitate a desired reaction is the main goal of many scientists. This award from the Organic Dynamics Program addresses this theme by tethering artificial catalytic units to gold surfaces and using alkanethio units to tune the inner catalytic environment. The education portion of the award will focus on preparing undergraduate and graduate students for their post-graduate careers by introducing two new courses. The first course will teach them how chemistry is involved in the everyday life and is titled, `Chemistry in Context`. For the second course, industrial scientists will be invited to give several lectures and perspectives of industrial careers.