Sequencing the Arabidopsis Genome

点击翻译按钮获取中文摘要

9631642 This award supports a consortium of three laboratories located at Stanford University, U.C. Berkley, and University of Pennsylvania. The long term goal of this project is to determine the total DNA sequence of the Arabidopsis thaliana genome. For the next three years, the specific goal of this consortium is to produce at least 5.2 Mb of finished sequences of DNA from chromosome 1. Additional important goal of this project is to apply the new high throughput DNA sequencing technologies to Arabidopsis genome sequencing. All sequences will be deposited in GenBank upon completion of each BAC or YAC clones. Unfinished sequence data will be made available on a WWW site to be set up at Stanford. Clones and other materials will be made available through the Arabidopsis Biological Resource Center at Ohio State. This award is one of the three awarded by the triagency (Department of Energy, National Science Foundation, and US Department of Agriculture) Arabidopsis thaliana genome research program. The activity of this consortium will be coordinated with the other groups engaged in large scale sequencing of the Arabidopsis genome. The results will contribute to determining the overall strategy for the completion of the sequence of the entire Arabidopsis genome. More importantly, the information and data produced will be useful to the general research community and will contribute to a rapid advance in plant biology.