Project Oriented Biochemistry Laboratory Course in a New B.S. Biochemistry Degree Program

新理学士项目导向的生物化学实验室课程

• 批准号: 9650559
• 负责人: Paul Craig
• 金额: $ 6万
• 依托单位: Rochester Institute of Tech
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 1996
• 资助国家: 美国
• 起止时间: 1996-07-01 至 1999-06-30
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=9650559&HistoricalAwards=false
• 关键词: Project; Oriented; Biochemistry; Laboratory; Course

A project-oriented laboratory has been designed to introduce students to the study of biochemistry as it is practiced. This course can be a capstone experience for students from a variety of majors, including those who enter the new Biochemistry program. In keeping with the department's focus on career education, this course is also preparing the students for future employment or graduate education. The specific goals of this proposal are to enable students to study the protein chemistry, enzymology, and molecular biology of a single enzyme in a series of integrated experiments using modern laboratory methods, including chromatography and capillary electrophoresis, and to supplement the learning experience of students enrolled in the biochemistry laboratory and lecture courses with effective molecular visualization and modeling tools. The students use a small computer network to prepare for experiments, using simulation software to access sequence homology databases over the Internet, to visualize proteins and nucleic acids, and to model small organic and biomolecules. The equipment is also being used by students and faculty in organic and analytical chemistry courses. The change in the biochemistry teaching lab from a disjointed collection of experiments using unrelated systems to a series of experiments focused around a single project is a model that can be readily adapted by other educators who can design their courses to focus on a single enzyme or protein with which they are most familiar.

一个以项目为导向的实验室被设计为向学生介绍生物化学的研究，因为它是实践。本课程可以为来自各种专业的学生，包括那些谁进入新的生物化学程序的顶点经验。为了与该部门对职业教育的关注保持一致，本课程也为学生未来的就业或研究生教育做好准备。 该提案的具体目标是使学生能够使用现代实验室方法（包括色谱法和毛细管电泳法）在一系列综合实验中学习单一酶的蛋白质化学，酶学和分子生物学，并补充学生在生物化学实验室和讲座课程中的学习经验，并提供有效的分子可视化和建模工具。 学生们使用一个小型计算机网络来准备实验，使用模拟软件通过互联网访问序列同源性数据库，可视化蛋白质和核酸，并模拟小的有机和生物分子。该设备也被学生和教师用于有机和分析化学课程。 生物化学教学实验室从使用不相关系统的脱节实验集合到围绕单个项目的一系列实验的变化是一种模型，可以很容易地被其他教育工作者所适应，他们可以设计他们的课程，专注于他们最熟悉的单一酶或蛋白质。