Introduction of Research-Based Instructional Laboratories Using GC-MS

介绍使用 GC-MS 的研究型教学实验室

• 批准号: 9650709
• 负责人: Lisa Lewis
• 金额: $ 4.27万
• 依托单位: Albion College
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 1996
• 资助国家: 美国
• 起止时间: 1996-06-01 至 1998-05-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=9650709&HistoricalAwards=false
• 关键词: Introduction; Research; Based; Instructional; Laboratories

This project supports the purchase of a gas chromatography/mass spectrometer (GC/MS) system, including both headspace equipment and an automatic sampler. This instrument is an integral part of new research-based experiments in general chemistry, chemical analysis, organic chemistry, and instrumentation and in undergraduate research. Chemical educators recognize the value of introducing students to research early in their careers, as it increases their interest and enthusiasm; however, few have implemented such experiments in the general chemistry laboratory. This project develops new research-based environmental experiments that can be introduced into the general chemistry and analytical chemistry curricula and serve to support the newly formed environmental science and studies concentrations. These experiments introduce students to the applicability of GC/MS to environmental study, particularly in the analysis of organics in natural water samples. This project further illustrates the usefulness of this technique by incorporating it into laboratory experiments that emphasize its importance in the bioanalytical (drug analysis, peptide structure) and organic fields. The GC/MS system has the capability to perform the analysis of volatile organic contaminants of water (headspace equipment), mass spectral library searches, single ion monitoring, and deconvolution (difference spectra) of overlapping peaks, and is able to facilitate the timely analysis of many samples (automatic sampler). This instrumentation can have a broad impact on science (chemistry, biology, and geology) majors and non-science-majors and especially on those students interested in environmental science.

该项目支持购买一套气相色谱/质谱仪系统，包括顶空设备和自动进样器。该仪器是普通化学，化学分析，有机化学和仪器仪表以及本科研究中新的研究型实验的组成部分。化学教育工作者认识到在职业生涯早期向学生介绍研究的价值，因为它增加了他们的兴趣和热情;然而，很少有人在普通化学实验室实施这样的实验。该项目开发了新的基于研究的环境实验，可以引入普通化学和分析化学课程，并用于支持新成立的环境科学和研究浓度。这些实验向学生介绍GC/MS在环境研究中的适用性，特别是在天然水样中有机物的分析中。该项目通过将其纳入实验室实验，进一步说明了该技术的实用性，强调了其在生物分析（药物分析，肽结构）和有机领域的重要性。 GC/MS系统能够分析水中的挥发性有机污染物（顶空设备）、质谱库搜索、单离子监测和重叠峰的去卷积（差谱），并能够促进对许多样品的及时分析（自动进样器）。这种仪器可以对科学（化学，生物学和地质学）专业和非科学专业，特别是对那些对环境科学感兴趣的学生产生广泛的影响。