REG: A High-Resolution CCD camera System for the Direct Measurement of the Conformations and the Transport Properties of a Single Macromolecule

REG：用于直接测量单个高分子的构象和传输特性的高分辨率 CCD 相机系统

• 批准号: 9700247
• 负责人: Denis Wirtz
• 金额: $ 2.5万
• 依托单位: Johns Hopkins University
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 1997
• 资助国家: 美国
• 起止时间: 1997-05-01 至 1998-04-30
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=9700247&HistoricalAwards=false
• 关键词: REG; Resolution; CCD; camera; System

ABSTRACT Proposal Number: CTS-9700247 Principal Inveqtigator: Wirtz This is a grant to purchase a low-intensity CCD camera system with a controller, monochromator and three-dimensional motor controlled microscope stage. This system will be used for imaging the transport of fluorescently-labeled macromolecules. An innovative magnetic force technique will be used to generate calibrated forces on fluorescently-labeled macromolecules, such as DNA, allowing for measurement of transport coefficients, e.g. relaxation time, friction coefficient and diffusion time. It is expected that this system will offer unique advantages for research in polymer and colloidal science and engineering.

摘要提案编号：CTS-9700247主要调查人：维尔茨 这是一个赠款购买一个低强度的CCD相机系统与控制器，单色仪和三维电机控制的显微镜载物台。 该系统将用于成像荧光标记的大分子的运输。一种创新的磁力技术将用于在荧光标记的大分子（如DNA）上产生校准的力，从而可以测量传输系数，例如弛豫时间、摩擦系数和扩散时间。 预计该系统将为聚合物和胶体科学与工程的研究提供独特的优势。