NSE/NIRT: Nanoscale Sensing of Single Cell Surface Receptor Affinity for Individual Ligands

NSE/NIRT：单细胞表面受体对单个配体的亲和力的纳米级传感

• 批准号: 0210718
• 负责人: Denis Wirtz
• 金额: $ 100万
• 依托单位: Johns Hopkins University
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2002
• 资助国家: 美国
• 起止时间: 2002-09-01 至 2006-08-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=0210718&HistoricalAwards=false
• 关键词: NSE; NIRT; Nanoscale; Sensing; Single

CTS-0210718Denis Wirtz, Johns Hopkins UniversityTitle: NIRT: Nanoscale Sensing of Single Cell Surface Receptor Affinity for Individual LigandsThis proposal was received in response to Nanoscale Science and Engineering initiative, NSF 01-157, category NIRT.The PI's are planning to use novel techniques based on the modification of an AFM tip to measure the affinity of a single cell surface receptor to its ligand. The approach is quite innovative and would result in significant new developments in this area.

dennis Wirtz, Johns Hopkins university，标题：NIRT：单细胞表面受体对单个配体亲和力的纳米级传感。该提案收到纳米级科学与工程计划的响应，NSF 01-157，类别NIRT。PI计划使用基于AFM尖端修饰的新技术来测量单个细胞表面受体与其配体的亲和力。这一方法具有相当的创新性，将在这一领域带来重大的新发展。