Development and Demonstration of Rapid Analysis of Single- Particle Composition Using Mass Spectrometry

使用质谱法快速分析单颗粒成分的开发和示范

• 批准号: 9703615
• 负责人: Anthony Wexler
• 金额: $ 7.97万
• 依托单位: University of Delaware
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 1997
• 资助国家: 美国
• 起止时间: 1997-05-15 至 1999-10-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=9703615&HistoricalAwards=false
• 关键词: Development; Demonstration; Rapid; Analysis; Single

9703615 Wexler This project supports the construction of a field-deployable Rapid Single-Particle Mass Spectrometer (RSMS). This instrument will be capable of providing chemical as well as size information on individual particles in the size range of 40 to 200 nm. This will be achieved by size selecting particles with a specially designed nozzle inlet, evaporating the particles using excimer laser radiation and analyzing the fragments using mass spectrometry. Chemical constituents such as organic carbon, elemental carbon, sulfates, methane sulfonates, and sodium chloride will be distinguishable. The information will be semi-quantitative due to shot-to-shot variations in signal intensity obtained with particles of identical composition, and due to a bias of the technique to surface species. However, chemometric data analysis techniques are capable of classifying the obtained spectra and extracting information on the aerosol composition and mixing state (external vs. internal). Once the assembly of the field-deployable instrument is completed, it will be tested at a local site to demonstrate the technique at ambient air conditions. The sizing technique will be calibrated and validated.

9703615 Wexler 该项目支持构建可现场部署的快速单粒子质谱仪 (RSMS)。该仪器将能够提供 40 至 200 nm 尺寸范围内单个颗粒的化学和尺寸信息。这将通过使用专门设计的喷嘴入口选择颗粒尺寸、使用准分子激光辐射蒸发颗粒并使用质谱分析碎片来实现。有机碳、元素碳、硫酸盐、甲磺酸盐和氯化钠等化学成分将是可区分的。由于使用相同成分的颗粒获得的信号强度的逐次变化以及由于该技术对表面物种的偏差，该信息将是半定量的。 然而，化学计量数据分析技术能够对获得的光谱进行分类并提取有关气溶胶成分和混合状态（外部与内部）的信息。 一旦现场部署仪器的组装完成，它将在当地进行测试，以在环境空气条件下演示该技术。尺寸确定技术将被校准和验证。