MCAA: Inbreeding Depression, Parental Behavior, and Mate Preference in Two Populations of the Prairie Vole

MCAA：两个草原田鼠种群的近交抑郁、父母行为和择偶偏好

• 批准号: 9728767
• 负责人: Zuleyma Tang-Martinez
• 金额: $ 4.58万
• 依托单位: University of Missouri-Saint Louis
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 1998
• 资助国家: 美国
• 起止时间: 1998-05-01 至 2000-04-30
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=9728767&HistoricalAwards=false
• 关键词: MCAA; Inbreeding; Depression; Parental; Behavior

PROPOSAL #: IBN 9728767 PI: Zyleyma Tang-Matrinez The proposed research will examine the genetic and behavioral effects of inbreeding, using the vole, Microtus ochrogaster as the model organism. The research will address: 1. The effects of inbreeding (defined as mating between close relatives) on the number of young produced per litter, as well as the weight, growth rates and survival of the pups. 2. The effects of inbreeding on parental behaviors. 3. Preferences of voles for related versus unrelated partners, or for inbred versus outbred partners. Systematic, quantitative behavioral observations along with weighing and monitoring of pups produced by inbred versus outbred matings will be employed to address the first two objectives. Mate choice experiments will demonstrate whether voles show preferences among four potential mates of different degrees of genetic relatedness ofrinbreeding. Inbreeding has detrimental effects in many species of animals, including humans. These effects may include decreased growth, reduce vigor, and the expression of genetic diseases of defects. Deficits in parental behaviors may cause or exacerbate some of these effects but almost nothing is currently known about the interactions between inbreeding and parental behavior. Similarly, little is known about the importance of inbreeding in determining mate choices. This research is expected to provide insights into possible behavioral effects of inbreeding in animals that could potentially be extrapolated to humans. Moreover, the information generated will be valuable to husbandry and conservation efforts that require the maintenance of genetic diversity in populations.

提案＃：IBN 9728767 PI：Zyleyma Tang-Matrinez提出的研究将使用Vole，Microtus ochrogaster作为模型生物体检查近交的遗传和行为效应。 这项研究将解决：1。近交（定义为近亲之间的交配）对幼犬产生的年轻人的数量以及幼犬的体重，生长速度和存活的影响。 2。近交对父母行为的影响。 3。田鼠对相关伴侣的偏好，或对近亲和近亲伴侣的偏好。 系统的定量行为观察以及对近交杂种和近代杂种材料产生的幼崽的称重和监测将采用来解决前两个目标。 伴侣选择实验将证明田鼠是否显示了四个不同程度的胞质相关性的潜在序列的偏好。 近亲繁殖在包括人类在内的许多动物中具有不利影响。这些影响可能包括降低生长，减少活力以及缺陷的遗传疾病的表达。 父母行为的缺陷可能会导致或加剧其中的一些影响，但目前几乎没有关于近交和父母行为之间的相互作用的了解。同样，对于确定伴侣选择的近交的重要性知之甚少。 预计这项研究将提供有关动物近交的可能行为影响的见解，这些行为影响可能会推断到人类。 此外，生成的信息将对需要维持人口遗传多样性的畜牧和保护工作有价值。