Adsorption of Polyampholytes

聚两性电解质的吸附

• 批准号: 9730777
• 负责人: Michael Rubinstein
• 金额: $ 16.5万
• 依托单位: University of North Carolina at Chapel Hill
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 1998
• 资助国家: 美国
• 起止时间: 1998-04-01 至 2001-03-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=9730777&HistoricalAwards=false
• 关键词: Adsorption; Polyampholytes

9730777 Rubinstein Charged polymers have recently attracted much attention due to their unique properties and their technological importance as rheology modifiers, dispersing aids, stabilizers, gelling agents, binders, etc. Polyampholytes are polymers carrying both positive and negative charges. Polymers carrying only positive or negative charge are called polyelectrolytes. The net charge of polyampholytes, e.g., proteins, is determined by the pH of the aqueous solution. Long-range Coulomb interactions are responsible for the rich behavior of these polymeric systems and for the difficulties in developing theories to describe them. While the coherent picture of polyelectrolytes and their interactions with surfaces is beginning to emerge, the theoretical description of polyampholytes is lagging far behind. In particular, there is no satisfactory theory of polyampholyte adsorption. Such a theory is necessary for understanding the details of interactions of latex particles stabilized by polyampholytes, adsorption of proteins on cell membranes, complexation of polyampholytes with polyelectrolytes and related problems. In the current research both analytical and numerical models of polyampholyte adsorption on charged surfaces will be constructed and solved. The problems addressed will include: the adsorption of a single polyampholyte chain, multi-chain adsorption, and the kinetics of polyampholyte adsorption. %%% Charged polymers have recently attracted much attention due to their unique properties and their technological importance as rheology modifiers, dispersing aids, stabilizers, gelling agents, binders, etc. Polyampholytes are polymers carrying both positive and negative charges. Polymers carrying only positive or negative charge are called polyelectrolytes. The net charge of polyampholytes, e.g., proteins, is determined by the pH of the aqueous solution. Long-range Coulomb interactions are responsible for the rich behavior of these polymeric systems and for the difficulties in developing theories to describe them. While the coherent picture of polyelectrolytes and their interactions with surfaces is beginning to emerge, the theoretical description of polyampholytes is lagging far behind. In particular, there is no satisfactory theory of polyampholyte adsorption. Such a theory is necessary for understanding the details of interactions of latex particles stabilized by polyampholytes, adsorption of proteins on cell membranes, complexation of polyampholytes with polyelectrolytes and related problems. In the current research both analytical and numerical models of polyampholyte adsorption on charged surfaces will be constructed and solved. The problems addressed will include: the adsorption of a single polyampholyte chain, multi-chain adsorption, and the kinetics of polyampholyte adsorption. ***

9730777 Rubinstein 带电聚合物由于其独特的性能和作为流变改性剂、分散助剂、稳定剂、胶凝剂、粘合剂等的技术重要性而最近引起了广泛关注。聚两性电解质是同时带有正电荷和负电荷的聚合物。 仅携带正电荷或负电荷的聚合物称为聚电解质。 聚两性电解质（例如蛋白质）的净电荷由水溶液的 pH 值决定。 长程库仑相互作用导致了这些聚合物系统的丰富行为，也导致了开发描述它们的理论的困难。 虽然聚电解质及其与表面相互作用的连贯图景开始出现，但聚两性电解质的理论描述却远远落后。 特别是，目前还没有令人满意的聚两性电解质吸附理论。 这种理论对于理解聚两性电解质稳定的乳胶颗粒相互作用的细节、细胞膜上蛋白质的吸附、聚两性电解质与聚电解质的络合以及相关问题是必要的。 在当前的研究中，将构建并求解带电表面上聚两性电解质吸附的分析模型和数值模型。 解决的问题包括：单链聚两性电解质的吸附、多链吸附以及聚两性电解质吸附的动力学。 %%% 带电聚合物由于其独特的性能和作为流变改性剂、分散助剂、稳定剂、胶凝剂、粘合剂等的技术重要性而最近引起了广泛关注。聚两性电解质是同时带有正电荷和负电荷的聚合物。 仅携带正电荷或负电荷的聚合物称为聚电解质。 聚两性电解质（例如蛋白质）的净电荷由水溶液的 pH 值决定。 长程库仑相互作用导致了这些聚合物系统的丰富行为，也导致了开发描述它们的理论的困难。 虽然聚电解质及其与表面相互作用的连贯图景开始出现，但聚两性电解质的理论描述却远远落后。 特别是，目前还没有令人满意的聚两性电解质吸附理论。 这种理论对于理解聚两性电解质稳定的乳胶颗粒相互作用的细节、细胞膜上蛋白质的吸附、聚两性电解质与聚电解质的络合以及相关问题是必要的。 在当前的研究中，将构建并求解带电表面上聚两性电解质吸附的分析模型和数值模型。 解决的问题包括：单链聚两性电解质的吸附、多链吸附以及聚两性电解质吸附的动力学。 ***