Meeting: Mechanisms of Nucleic Acid Enzymes, June 13-18, 1998, at Saxton's River, Vermont

9802699贝尔福这次会议将讨论作用于脱氧核糖核酸和核糖核酸的酶的结构、机制和生物学作用。包括作用于核酸的蛋白质酶和核糖核酸酶。这次会议旨在吸引来自美国和海外的广泛的跨学科科学家。这些人包括化学家、生物化学家、结构和分子生物学家、遗传学家和细胞生物学家。这次会议将是美国实验生物学学会联合会(FASE B)就这一一般性主题举行的第三次会议，上一次是在1996年。从那时起，人们对这些分子的结构、机制和调节潜力的了解大大扩展。因此，这次FASB会议既及时又具有时代性。主办方已经为九场会议选出了讨论领袖，并为另一场会议选出了一名主旨发言人。讲者从诺贝尔奖获得者，到注定要在其专业领域取得进展的有成就的年轻科学家。会议将讨论的主题包括核酸酶的结构和功能；合成酶和新的活性；可移动元素的核酸内切酶和整合酶；RNA的催化和整合；重组和修复；连接酶、拓扑异构酶和封闭酶；复制蛋白质；以及基因组学。此外，还将举行海报竞赛；获奖海报的学生和博士后将有机会发表演讲。会议将集中讨论研究核酸基本特征的有力和富有成果的方法，并将成为研究与核酸相互作用的酶的多学科论坛。虽然也举行了以这一一般领域的各种专业为中心的会议，但这种特殊的跨学科混合主题是史无前例的，有望为对基础研究和生物技术感兴趣的科学家之间进行丰富的科学交流提供一个独特的机会。

9802699 Belfort This meeting will cover the structure, mechanism, and biological roles of enzymes that act on DNA and RNA. Included are both protein and RNA enzymes that act on nucleic acids. The meeting is designed to attract a broad cross-disciplinary spectrum of scientists from the U.S. and abroad. These include chemists, biochemists, structural and molecular biologists, geneticists and cell biologists. This meeting will be the third held by the Federation of American Societies of Experimental Biology (FASEB) on this general topic, the last having been in 1996. Since then, the understanding of the structure, mechanism and regulatory potential of these molecules has expanded greatly . This FASEB meeting is therefore both timely and topical. The organizers have selected discussion leaders for the nine sessions and a keynote speaker for an additional session. Speakers range from Nobel prize-winners at the forefront of their fields to accomplished young scientists destined to make inroads in their specialities.The topics to be covered at the meeting include nuclease structure & function; synthetic enzymes and novel activities; endonucleases and integrases of mobile elements; catalysis of and by RNA; recombination and repair; ligases, topoisomerases, and capping enzymes; replication proteins; and genomics. In addition, there will be a poster competition; students and post-docs with winning posters will be given the opportunity to present a talk. The meeting will provide a focus for powerful and fruitful approaches to studying fundamental features of nucleic acids and will serve as a multidisciplinary forum for the study of enzymes which interact with nucleic acids. Although meetings centering on various specialities of this general field are also held, this particular interdisciplinary mix of topics is unprecedented and promises a unique opportunity for fertile scientific exchange among scientists with interests in basic research and biotechnology.