H-Bonding Control of Molecular Self-Assembly

本研究的重点将围绕三大主题展开。首先，在作为超临界二氧化碳衍生凝胶合成的氢键稳定聚集体的形成中，将建立广泛的结构-活性关系。其次，官能团将被整合到聚集体中，从而实现新的识别和催化性能的潜力。第三，将研究在溶液中具有可控孔径的有序组装，并将其应用于制备超临界二氧化碳衍生气凝胶。有机化学和高分子化学项目支持耶鲁大学化学系的安德鲁·D·汉密尔顿博士的研究。汉密尔顿教授将专注于氢键的发展，以此作为控制溶液、固体以及干凝胶和气凝胶形成中分子聚集体的结构和性质的途径。这种方法很可能会产生用于现实世界应用的材料。

The focus of this research will follow three major themes. First, extensive structure activity relationships will be established in the formation of hydrogen bond stabilized aggregates synthesized as supercritical carbon dioxide-derived gels . Second, functionality will be incorporated into the aggregates so that the potential for novel recognition and catalytic properties can be realized. Third, ordered assemblies with controlled pore size in solution will be investigated with application to the preparation of supercritical carbon dioxide-derived aerogels. With this renewal award, the Organic and Macromolecular Chemistry Program is supporting the research of Dr. Andrew D. Hamilton from the Department of Chemistry at Yale University. Professor Hamilton will focus his work on the development of hydrogen bonding as a route to controlling the structure and properties of molecular aggregates in solution, in the solid state and in the formation of both xerogels and aerogels. It is probable that materials for real-world applications will arise from this approach.