13th International Symposium on Flavins and Flavoproteins to be held August 29-September 4, 1999 at the University of Konstanz, Konstanz, Germany

黄素和黄素蛋白是一个广泛的领域，但定义明确而简单。它涵盖了与基于异四氧嘧啶核的化合物的化学和生物学以及极少数密切相关的结构有关的所有方面的工作。由于黄素作为一种修复体具有非凡的多功能性，它参与了各种重要的生物氧化和还原过程，这一领域继续迅速扩大。对黄素的兴趣从理论化学到医学方面都有。第13届黄素和黄蛋白国际研讨会于1999年8月29日至9月4日在德国康斯坦茨大学举行，这是自1965年以来每三年举办一次的系列研讨会之一。上一次专题讨论会是1996年在阿尔伯塔省卡尔加里举行的。由于这一领域的研究持续和加快步伐，定期举行会议是很重要的。回顾讲座将覆盖整个领域，这次会议应该让来自世界各地的来自不同学科的科学家聚集在一起，并促进有价值的讨论和信息交流。核黄素(维生素B2)是人体必需的营养物质，这一要求的生物化学基础可以用以下事实来解释：三黄素衍生物(FMN和FAD，缩写为FMN和FAD)是人体新陈代谢和营养中重要的许多化学过程的必需的醇酶。在许多情况下，相应的黄素酶直接或间接地参与将食物中的化学能转化为三磷酸腺苷，三磷酸腺苷是基本生化功能所需的储存能量的细胞形式。因此，对黄素和黄素蛋白的研究对人体生理学有直接影响，自1965年以来，来自美国和世界各地的研究人员每三年举行一次会议，分享和讨论他们在黄素和黄素蛋白研究方面的最新发现。1999年，第13届黄素和黄素蛋白国际研讨会在德国康斯坦茨举行；该NSF奖提供的资金专门用于帮助来自美国的年轻研究人员(主要是博士生和研究生)参加这次会议。

9900534ClaiborneThe area of flavins and flavoproteins is a broad, but clearly andsimply defined one. It covers all aspects of work pertaining to thechemistry and biology of compounds based on the isoalloxazine nucleusand on a very few closely related structures. Because of theextraordinary versatility of flavin as a prosthetic group and itsinvolvement in a variety of important biological oxidation and reductionprocesses, this area continues to expand rapidly. Interest in flavinsranges from theoretical chemistry to medical aspects. The 13thInternational Symposium on Flavins and Flavoproteins is atthe University of Konstanz, Konstanz, Germany, August 29-September 4,1999, as one of a series which has been organized at 3-year intervalssince 1965. The last symposium was held in Calgary, Alberta in 1996.Because of the continued and increasing pace of research in this area,it is important that regularly scheduled meetings be held. Reviewlectures will cover the entire field and the meeting should bringtogether scientists from all over the world from a wide variety ofdisciplines, and promote valuable discussion and exchange ofinformation. In addition, it should serve the purposes of keepingexisting workers fully up to date with all aspects of the subject and ofinitiating young investigators into this important area of research.Riboflavin (vitamin B2) is an essential nutrient in humans; thebiochemical basis for this requirement can be explained by the fact thatriboflavin derivatives (FMN and FAD, as abbreviated) serve as essentialcoenzymes for a large number of chemical processes important in humanmetabolism and nutrition. In many cases the corresponding flavo-enzymesare involved in the conversion of chemical energy from foodstuffs,directly or indirectly, into ATP, which is the cellular form of storedenergy required for essential biochemical functions. Therefore thestudy of flavins and flavoproteins has direct consequences for humanphysiology and since 1965, researchers from the U.S. and around the worldhave convened every three years to share and discuss their latestfindings in flavin and flavoprotein research. In 1999 the 13thInternational Symposium on Flavins and Flavoproteins is inKonstanz, Germany; the funds provided by this NSF award are usedspecifically to assist young investigators (primarily Ph.D. students andpost-graduate fellows) from the U.S. in attending this conference.