Digestive Specializations for Herbivory in Marine Fishes: Genetic Adaptation and Phenotypic Plasticity in Gut Structure and Function in Pricklebacks
海洋鱼类草食性的消化特化:刺鱼肠道结构和功能的遗传适应和表型可塑性
基本信息
- 批准号:9906857
- 负责人:
- 金额:$ 45万
- 依托单位:
- 依托单位国家:美国
- 项目类别:Continuing Grant
- 财政年份:2000
- 资助国家:美国
- 起止时间:2000-01-01 至 2003-04-30
- 项目状态:已结题
- 来源:
- 关键词:
项目摘要
Horn 9906857The requirements for herbivory in terms of gut structure and function remain poorly understood for marine fishes. The impetus for this research can be framed as a question: What does it take to be a herbivore? To answer this question, feeding experiments and accompanying histological and enzymatic analyses at different levels of biological organization will be performed. The work involves a two-part investigation addressing genetic adaptation and phenotypic plasticity of the digestive system in four related species of marine fishes. In the first part of the project, the objective is to test whether there are genetically programmed changes in gut structure and function that precede an ontogenetic dietary shift from carnivory to herbivory. To meet this objective, the activity, location, concentration and gene expression of a broad array of digestive and absorptive enzymes will be determined in the target fishes that have been fed a consistent animal diet during an interval in which two of the species naturally switch from carnivory to herbivory and the other two naturally remain carnivorous. In the second part of the project, the objective is to assess the degree of phenotypic plasticity in gut structure and function shown by carnivorous and herbivorous fishes. To meet this objective, gut structure and digestive enzyme adjustments and body composition changes will be determined during experiments in which the four target species are fed both a plant and an animal diet. The fishes chosen for this study are members of adjacent clades in a larger clade of a phylogeny that has been proposed for the family (Stichaeidae, pricklebacks) to which these species belong. These related taxa are viewed as model species for this type of research because all four begin life as carnivores, but two switch to herbivory as small juveniles while the other two remain carnivorous throughout life. The histological and enzymatic data obtained in the two-part study will be mapped as phenotypic traits onto the stichaeid phylogenetic tree using comparative biology methods to see whether adaptations for herbivory and the evolutionary trajectory of diet change can be inferred for this family of fishes. The research has the potential to make a substantial contribution to the understanding of gut structure and function in marine fishes and offers a model approach that can be applied to other marine systems. The use of an array of powerful in situ histochemical and molecular techniques in the context of both ontogeny and phylogeny should advance the knowledge of digestive processes among marine fishes in general and broaden the perspective on marine vertebrate herbivores. The project will also help advance science education and develop human resources by involving persons from a full range of academic levels and from different gender and ethnic backgrounds. Teaching, training and learning will be enhanced by this diversity of involvement and by the acquisition of new laboratory equipment.
喇叭 9906857海洋鱼类在肠道结构和功能方面对食草动物的要求仍然知之甚少。这项研究的动力可以归结为一个问题:成为食草动物需要什么?为了回答这个问题,将在不同的生物组织水平上进行饲养实验和伴随的组织学和酶分析。这项工作包括两部分的调查,解决遗传适应和表型可塑性的消化系统在四个相关的海洋鱼类物种。在该项目的第一部分,目的是测试是否有遗传编程的肠道结构和功能的变化,之前的个体发育饮食从食肉动物到草食动物的转变。为了实现这一目标,活性,位置,浓度和基因表达的消化和吸收酶的广泛阵列将被确定在目标鱼,已经喂了一个一致的动物饮食期间的间隔,其中两个物种自然切换从肉食性到草食性和其他两个自然保持肉食性。在该项目的第二部分,目标是评估食肉和草食性鱼类肠道结构和功能的表型可塑性程度。为了实现这一目标,将在实验期间确定肠道结构和消化酶的调整以及身体组成的变化,在实验中,四个目标物种被喂食植物和动物饮食。本研究所选择的鱼类是相邻的分支在一个较大的分支,已提出的家庭(Stichaeidae,棘鱼),这些物种所属的。这些相关的分类群被视为这类研究的模式物种,因为所有四个开始生活作为食肉动物,但两个切换到草食性作为小的青少年,而其他两个保持食肉整个生命。在两部分的研究中获得的组织学和酶的数据将映射到stichaeid系统发育树的表型特征,使用比较生物学方法,看看是否适应草食性和饮食变化的进化轨迹可以推断这个家庭的鱼。这项研究有可能对海洋鱼类肠道结构和功能的理解做出重大贡献,并提供了一个可应用于其他海洋系统的模型方法。使用一系列强大的原位组织化学和分子生物学技术的背景下,个体发育和胚胎发育,应推进海洋鱼类之间的消化过程的知识,并拓宽海洋脊椎动物草食动物的前景。该项目还将通过让来自各个学术水平以及不同性别和种族背景的人参与进来,帮助推进科学教育和开发人力资源。教学,培训和学习将通过这种参与的多样性和新的实验室设备的采购得到加强。
项目成果
期刊论文数量(0)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
数据更新时间:{{ journalArticles.updateTime }}
{{
item.title }}
{{ item.translation_title }}
- DOI:
{{ item.doi }} - 发表时间:
{{ item.publish_year }} - 期刊:
- 影响因子:{{ item.factor }}
- 作者:
{{ item.authors }} - 通讯作者:
{{ item.author }}
数据更新时间:{{ journalArticles.updateTime }}
{{ item.title }}
- 作者:
{{ item.author }}
数据更新时间:{{ monograph.updateTime }}
{{ item.title }}
- 作者:
{{ item.author }}
数据更新时间:{{ sciAawards.updateTime }}
{{ item.title }}
- 作者:
{{ item.author }}
数据更新时间:{{ conferencePapers.updateTime }}
{{ item.title }}
- 作者:
{{ item.author }}
数据更新时间:{{ patent.updateTime }}
Michael Horn其他文献
Symbolic Relations in Collaborative Coding: How Children and Parents Map Across Symbol Systems While Coding Robots
协作编码中的符号关系:孩子和家长在对机器人进行编码时如何跨符号系统进行映射
- DOI:
- 发表时间:
2021 - 期刊:
- 影响因子:0
- 作者:
Naomi Polinsky;Brian Andrus;Michael Horn;D. Uttal - 通讯作者:
D. Uttal
Neuregelung der Verlängerung von Zulassungen und Einführung der Sunset-Clause
- DOI:
10.1007/s00103-008-0580-z - 发表时间:
2008-07-04 - 期刊:
- 影响因子:1.500
- 作者:
Michael Horn - 通讯作者:
Michael Horn
Protective effect of the specific endothelin-1 antagonist BQ610 on mechanical function and energy metabolism during ischemia/reperfusion injury in isolated perfused rat hearts.
特异性内皮素-1 拮抗剂 BQ610 对离体灌注大鼠心脏缺血/再灌注损伤期间机械功能和能量代谢的保护作用。
- DOI:
10.1097/00005344-199604000-00006 - 发表时间:
1996 - 期刊:
- 影响因子:3
- 作者:
Barbara Illing;Michael Horn;Hong Han;Susanne Hahn;Peter Bureik;Georg Ertl;Stefan Neubauer - 通讯作者:
Stefan Neubauer
FRI-332 - Anti-nucleosome antibodies as an important marker to distinguish between autoimmune hepatitis and drug-induced liver injury
- DOI:
10.1016/s0168-8278(23)01080-2 - 发表时间:
2023-06-01 - 期刊:
- 影响因子:
- 作者:
Mirjam Kolev;Guido Stirnimann;Henning Nilius;Juliette Schlatter;Michèle Freiburghaus;Michael Nagler;Michael Horn;Nasser Semmo - 通讯作者:
Nasser Semmo
A hemicellulose-first approach: one-step conversion of sugarcane bagasse to xylooligosaccharides over activated carbon modified with tandem plasma and acid treatments
半纤维素优先方法:在经串联等离子体和酸处理改性的活性炭上一步将甘蔗渣转化为低聚木糖
- DOI:
10.1039/d2gc01303g - 发表时间:
2022-01-01 - 期刊:
- 影响因子:9.200
- 作者:
Shahrooz Rahmati;Luqman Atanda;Michael Horn;K. shan De Athukoralalage Don;Javier Jimenez Forero;Lalehvash Moghaddam;Deepak Dubal;Kostya (Ken) Ostrikov;William O.S. Doherty - 通讯作者:
William O.S. Doherty
Michael Horn的其他文献
{{
item.title }}
{{ item.translation_title }}
- DOI:
{{ item.doi }} - 发表时间:
{{ item.publish_year }} - 期刊:
- 影响因子:{{ item.factor }}
- 作者:
{{ item.authors }} - 通讯作者:
{{ item.author }}
{{ truncateString('Michael Horn', 18)}}的其他基金
Designing and Studying Collaborative Coding Experiences for Middle School Computer Science Education
设计和研究中学计算机科学教育的协作编码体验
- 批准号:
2342632 - 财政年份:2024
- 资助金额:
$ 45万 - 项目类别:
Standard Grant
Supporting Computational Literacy by Designing a Collaborative Platform at the Intersection of Music and Code
通过设计音乐和代码交叉点的协作平台来支持计算素养
- 批准号:
2119701 - 财政年份:2021
- 资助金额:
$ 45万 - 项目类别:
Standard Grant
Broadening Participation in Computer Science Through Programming and the Arts Across Learning Spaces
通过跨学习空间的编程和艺术扩大对计算机科学的参与
- 批准号:
1837661 - 财政年份:2018
- 资助金额:
$ 45万 - 项目类别:
Standard Grant
Collaborative Research: Mixing Learning Experiences for Computer Programming Accorss Museums, Classrooms, and the Home Using Computational Music
协作研究:使用计算音乐在博物馆、教室和家庭中混合计算机编程的学习体验
- 批准号:
1612619 - 财政年份:2016
- 资助金额:
$ 45万 - 项目类别:
Standard Grant
CAREER: Blocks, Stickers, and Puzzles: Rethinking Computational Literacy Experiences in Informal Environments
职业:积木、贴纸和谜题:重新思考非正式环境中的计算素养体验
- 批准号:
1451762 - 财政年份:2015
- 资助金额:
$ 45万 - 项目类别:
Continuing Grant
EXP: Augmenting Household Technologies for Learning and Whole Family Participation: Heating and Cooling Control as an Exploratory Case
EXP:增强家庭技术以促进学习和全家人参与:供暖和制冷控制作为探索性案例
- 批准号:
1123574 - 财政年份:2011
- 资助金额:
$ 45万 - 项目类别:
Standard Grant
SGER: Seed Dispersal by Fruit-eating Fish in a Costa Rican Rain Forest
SGER:哥斯达黎加雨林中食果鱼的种子传播
- 批准号:
9106980 - 财政年份:1991
- 资助金额:
$ 45万 - 项目类别:
Standard Grant
A Model of Marine Fish Herbivory in Cold Waters Dietary Choice, Growth, Food Processing and Metabolism of Temperate-Zone Seaweed-Eating Fishes
冷水海洋鱼类食草模型温带海藻鱼类的食性选择、生长、食物加工和代谢
- 批准号:
8716368 - 财政年份:1988
- 资助金额:
$ 45万 - 项目类别:
Continuing Grant
Feeding Ecology and Digestive Physiology of Herbivorous Fishes in Temperate Marine Waters
温带海水草食性鱼类的摄食生态学和消化生理学
- 批准号:
8218797 - 财政年份:1983
- 资助金额:
$ 45万 - 项目类别:
Continuing Grant
Feeding Ecology and Digestive Physiology of Herbivorous Fishes in Temperate Marine Waters
温带海水草食性鱼类的摄食生态学和消化生理学
- 批准号:
8109599 - 财政年份:1981
- 资助金额:
$ 45万 - 项目类别:
Standard Grant
相似海外基金
Doctoral Dissertation Research: The Evolution of Locomotor Specializations in the Context of Adaptive Plasticity
博士论文研究:自适应可塑性背景下运动专业化的演变
- 批准号:
2341351 - 财政年份:2024
- 资助金额:
$ 45万 - 项目类别:
Standard Grant
Circuit Specializations of Cerebellar Molecular Layer Interneurons
小脑分子层中间神经元的电路特化
- 批准号:
10722374 - 财政年份:2023
- 资助金额:
$ 45万 - 项目类别:
NSF PRFB FY 2023: The evolution and ecological drivers of retinal specializations in fish
NSF PRFB 2023 财年:鱼类视网膜特化的演变和生态驱动因素
- 批准号:
2305797 - 财政年份:2023
- 资助金额:
$ 45万 - 项目类别:
Fellowship Award
NSF Postdoctoral Fellowship in Biology: Ordered Evolution and Muscle-Specific Specializations of Constriction Behaviors in Snakes
美国国家科学基金会生物学博士后奖学金:蛇收缩行为的有序进化和肌肉特异性
- 批准号:
2209023 - 财政年份:2023
- 资助金额:
$ 45万 - 项目类别:
Fellowship Award
Visual pathway cooperation to align viewing strategies and processing specializations for predation
视觉通路合作,以调整捕食的观察策略和处理专业化
- 批准号:
10467484 - 财政年份:2022
- 资助金额:
$ 45万 - 项目类别:
Visual pathway cooperation to align viewing strategies and processing specializations for predation
视觉通路合作,以调整捕食的观察策略和处理专业化
- 批准号:
10599366 - 财政年份:2022
- 资助金额:
$ 45万 - 项目类别:
Development of Specializations Required for Temporal Coding in Octopus Cells
章鱼细胞时间编码所需专业化的发展
- 批准号:
10384008 - 财政年份:2021
- 资助金额:
$ 45万 - 项目类别:
Development of Specializations Required for Temporal Coding in Octopus Cells
章鱼细胞时间编码所需专业化的发展
- 批准号:
10541129 - 财政年份:2021
- 资助金额:
$ 45万 - 项目类别:
Dimensions US Sao Paulo: Evolutionary and genetic origins of diverse trophic specializations in blow flies
Dimensions 美国圣保罗:丽蝇不同营养特化的进化和遗传起源
- 批准号:
2030345 - 财政年份:2021
- 资助金额:
$ 45万 - 项目类别:
Continuing Grant
Development of Specializations Required for Temporal Coding in Octopus Cells
章鱼细胞时间编码所需专业化的发展
- 批准号:
10686066 - 财政年份:2021
- 资助金额:
$ 45万 - 项目类别: