Improvement of Molecular Biology Components of the Human Biology Curriculum: Incorporation of a Research-Based Learning Approach

根据霍普学院的凯瑟琳马德尔提供的材料，（建立和维持本科生研究计划）和德鲁大学的路易丝·坦普尔和威斯康星州格林湾大学的布赖恩·默克尔（如何在小型文理学院作为研究人员生存）在1998年的万花筒项目国民大会和一个小型试点项目中，学生们正在使用研究项目的方法来学习生物学。 学生们正在通过设计和利用基因表达的复杂技术（组织冷冻切片，免疫细胞化学，酶细胞化学和原位杂交）进行研究实验来提高他们的科学推理和分析能力。 一些球场受到影响。 发育生物学的学生是：设计实验来分析胚胎发生过程中基因的组织特异性表达;进行标记实验，以便在胚胎切片中观察这种表达;使用图像分析站记录和分析他们的数据;并在学期末的学生海报会议上传播他们的科学数据。 细胞生物学的学生进行类似的实验室项目，涉及酶细胞化学。 分子生物学、免疫学、显微解剖学和分子遗传学课程也在采用新方法，并使用新设备。

In an approach adapted from materials presented by Catherine Mader of Hope College (Building and Sustaining an Undergraduate Research Program) and Louise Temple of Drew University and Brian Merkle of University of Wisconsin Green Bay (How to Survive as a Researcher in a Small Liberal Arts College) at the 1998 Project Kaleidoscope National Assembly and a small pilot project, students are using a research project approach to learning biology. Students are sharpening their scientific reasoning and analytical skills by designing and conducting research experiments utilizing sophisticated techniques for gene expression (tissue cryosectioning, immunocytochemistry, enzyme cytochemistry, and in situ hybridization). A number of courses are affected. Developmental Biology students are: designing experiments to analyze the tissue-specific expressions of a gene during embryogenesis; performing labeling experiments for visualization of this expression in embryo sections; recording and analyzing their data using an image analysis station; and disseminating their scientific data at a student poster session at the end of the semester. Cell Biology students perform similar laboratory projects involving enzyme cytochemistry. Molecular Biology, Immunology, Microscopic Anatomy and Molecular Genetics courses are also adapting the new approach and implementing use of the new equipment.