Improvement of Undergraduate Preparation in Molecular Biology

分子生物学本科准备工作的改进

• 批准号: 0088757
• 负责人: LaJoyce Debro
• 金额: $ 3.97万
• 依托单位: Jacksonville State University
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2001
• 资助国家: 美国
• 起止时间: 2001-05-01 至 2005-05-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=0088757&HistoricalAwards=false
• 关键词: Improvement; Undergraduate; Preparation; Molecular; Biology

Biological Sciences (61)This project is using inquiry-based cooperative learning and research training in a culturally diverse setting to 1) improve undergraduate preparation in Molecular Biology; 2) enhance application of the scientific method; and 3) encourage team projects that promote interactions among culturally diverse learners. Funds are being used to upgrade a sequence of two courses and undergraduate research facilities. Specifically an existing course in MolecularBiology is being modified to involve students in an inquiry based cooperative learning project where students learn from their peers and the professor serves as a facilitator in the process. The effort is an adaptation of a laboratory manual "Unraveling DNA," developed with NSF support. The laboratory component of the course is being expanded to include subcloning and sequence analysis of the luxA gene from the Lux operon that is cloned in the existing course. Students, working in groups, use the polymerase chain reaction and DNA sequencing and analysis to study their clones. In the second course, Advanced Topics, cooperative learning continues as students read and discuss original research articles that assist them in applying the principles and techniques of molecular biology and the scientific method to a novel situation. Students develop and submit a research proposal to external sources or the established University student/faculty research program for funding consideration. Students complete the proposed research as an undergraduate research project and present the results at the annual student symposium as either a poster or an oral presentation. The goals of the project are consistent with the department's mission that promotes cooperative learning and undergraduate research as a capstone course. Funds are being used for instrumentation, course development and evaluation.

生物科学(61)这个项目在不同文化背景下使用基于探究的合作学习和研究培训，以1)改善分子生物学本科生的准备工作；2)加强科学方法的应用；3)鼓励团队项目，促进不同文化背景的学习者之间的互动。资金正用于升级一系列两门课程和本科生研究设施。具体地说，正在修改分子生物学的一门现有课程，让学生参与一个基于探究的合作学习项目，在这个项目中，学生向同龄人学习，教授在这个过程中担任促进者。这项工作是对国家科学基金会支持下开发的实验室手册《解开DNA》的改编。本课程的实验室部分正在扩展，以包括对现有课程中克隆的Lux操纵子的LuxA基因进行亚克隆和序列分析。学生们分组工作，使用聚合酶链式反应和DNA测序和分析来研究他们的克隆。在第二门课程高级主题中，合作学习继续进行，学生们阅读和讨论帮助他们将分子生物学的原理和技术以及科学方法应用于新情况的原创研究文章。学生制定并向外部来源或已建立的大学学生/教师研究计划提交研究建议，以供资金考虑。学生完成建议的研究作为本科生的研究项目，并在年度学生研讨会上以海报或口头演示的形式展示结果。该项目的目标与系的使命是一致的，即促进合作学习和本科生研究作为顶峰课程。资金正用于工具编制、课程开发和评估。