Molecular Structure and Function in an Undergraduare Curriculum (Proof of Concept)

本科课程中的分子结构和功能（概念证明）

• 批准号: 9952693
• 负责人: Tim Herman
• 金额: $ 7.49万
• 依托单位: Milwaukee School of Engineering
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2000
• 资助国家: 美国
• 起止时间: 2000-02-01 至 2001-01-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=9952693&HistoricalAwards=false
• 关键词: Molecular; Structure; Function; Undergraduare; Curriculum

Biological Sciences (61)A student-focussed, guided inquiry approach to teaching concepts of molecular structure and function is being developed using accurate, three dimensional physical models of protein structure. The physical models provide students with a solid base upon which to construct their knowledge of the molecular world. This approach is being tested both in long-standing introductory biology and chemistry courses, where these models and accompanying computer visualization tools will be used to complement and extend existing courses, and in a new upper level biochemistry course specifically designed around this pedagogical approach. The pedagogical model employed enables students to discover and construct their own knowledge by relating abstract concepts as much as possible to real world examples. Students use the physical model to translate the abstract concept of a protein into something tangible and tactilely significant. Students then formulate their own questions regarding the structure and functional features of a model protein and, in a guided but open-ended laboratory experience, explore the answers to their questions.

生物科学（61）正在开发一种以学生为中心，引导探究的方法来教授分子结构和功能的概念，使用蛋白质结构的精确三维物理模型。 物理模型为学生提供了一个坚实的基础，在此基础上构建他们的分子世界的知识。 这种方法正在长期的生物学和化学入门课程中进行测试，这些模型和附带的计算机可视化工具将用于补充和扩展现有课程，并在新的高级生物化学课程中专门围绕这种教学方法设计。 所采用的教学模式使学生能够通过尽可能多地将抽象概念与真实的世界的例子联系起来来发现和构建自己的知识。学生使用物理模型将蛋白质的抽象概念转化为有形和有意义的东西。 然后，学生制定自己的问题，关于模型蛋白质的结构和功能特征，并在一个指导，但开放式的实验室经验，探索他们的问题的答案。