SBIR Phase I: Development of a Differential Long-Path Spectrophotometer for On-line Measurements of Controlled Halogenated Organic Compounds in Potable Water

SBIR 第一阶段：开发用于在线测量饮用水中受控卤代有机化合物的差分长光程分光光度计

• 批准号: 9960701
• 负责人: Yogesh Agrawal
• 金额: $ 9.9万
• 依托单位: Sequoia Scientific, Inc.
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2000
• 资助国家: 美国
• 起止时间: 2000-01-01 至 2000-06-30
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=9960701&HistoricalAwards=false
• 关键词: SBIR; Phase; Development; Differential; Long

This Small Business Innovation Research Phase I project is concerned with the development of a Differential Long-path Spectrophotometer (DLS) for on-line measurements of halogenated organic species that are formed when potable water is disinfected (disinfection by-products, or DBPs). The instrument to be developed will eliminate major difficulties that water utilities currently face in their efforts to monitor and control DBPs. Specifically, whereas at present the analyses of interest are extremely costly and time-consuming, the new instrument will provide inexpensive and virtually instantaneous data, allowing utilities to monitor DBP formation in real time and to respond rapidly if DBP concentrations exceed acceptable bounds. The key technical feature of the DLS will be its ability to measure, with high precision, the relatively small changes in light absorbance by natural organic matter (NOM) caused by addition of chlorine to potable water (the differential absorbance). These changes will be correlated with the concentration of individual DBPs formed and of a composite parameter characterizing the total chlorinatedDBP concentration in solution, the total organic halogen (TOX). The key concept behind DLS is the extremely strong correlation, first identified by sub-contractors of this proposal, between the differential absorbance and the concentration of the target compounds. The DLS measurements needed to quantify the formation of DBPs are fast and inexpensive. They do not involve the use of any toxic chemicals or organic solvents. Thus, the DLS instrument will address social, engineering and analytical needs and will fill an existing niche in the market of analytical instrumentation. The Phase I project will include the design and assembly of one or two working DLS prototypes and initial testing of the prototype(s) under laboratory and field conditions.Phase II will involve full development and tests of the prototypes and extensive evaluation of the performance parameters (e.g., sensitivity, dynamic range, stability), and will result in a tested and calibrated prototype device. Sequoia intends to carry out the transition to market.

这个小企业创新研究第一阶段项目涉及差分长光程分光光度计（DLS）的开发，用于在线测量饮用水消毒时形成的卤代有机物（消毒副产品或DBPs）。 即将开发的工具将消除供水公司目前在监测和控制消毒副产物方面面临的主要困难。 具体地说，尽管目前感兴趣的分析是极其昂贵和耗时的，但新仪器将提供廉价和几乎瞬时的数据，允许公用事业公司真实的时间监测DBP的形成，并在DBP浓度超过可接受的范围时迅速作出反应。 DLS的主要技术特点是能够高精度地测量天然有机物（NOM）因向饮用水中添加氯而引起的相对较小的吸光度变化（差分吸光度）。 这些变化将与形成的单个DBP的浓度和表征溶液中总的chlorinatedDBP浓度的复合参数（总有机卤素（TOX））相关。 DLS背后的关键概念是差异吸光度和目标化合物浓度之间的极强相关性，这是由该提案的分包商首先确定的。 量化DBP形成所需的DLS测量快速且廉价。 它们不涉及使用任何有毒化学品或有机溶剂。 因此，DLS仪器将满足社会、工程和分析需求，并将填补分析仪器市场的现有空白。 第一阶段项目包括设计和组装一个或两个可工作的DLS原型，并在实验室和现场条件下对原型进行初步测试。第二阶段将涉及原型的全面开发和测试，以及对性能参数（例如，灵敏度、动态范围、稳定性），并将产生经过测试和校准的原型设备。 红杉打算进行向市场的过渡。