SBIR Phase I: Development of a Hybrid Imaging Avalanche Photodiode

这一阶段的小型企业创新研究项目旨在开发一种低成本的单光子成像探测器。该探测器将支持需要快速获取从超低能级光获得的图像的诊断系统。例如：食品、饮料、制药和半导体行业液体中细菌和酵母菌污染的检测；以及基因特异性活动筛查的临床诊断。该项目的第一阶段将演示该设备的概念。第二阶段将开发一种支持大规模生产的制造工艺，并将启动一种或多种特定分析仪器的定制设计。以当前技术成本的一小部分提供合适的检测器，将有助于广泛采用和开发比当前常见做法更快、更准确的分析方法。美国的工业将受益于依赖于这些检测方法的过程中质量和生产率的提高，生产这些检测方法的公司将享受对其产品需求的增长。

This Phase I Small Business Innovation Research project aims to develop a low cost single optical photon imaging detector. This detector will support diagnostic systems needing rapidly acquired images obtained from ultra-low levels of light. Examples include: assays for bacterial and yeast contamination in fluids in the food, beverage, pharmaceutical and semiconductor industries; and clinical diagnostics for gene-specific activity screens. Phase I of this project will demonstrate the device concept. Phase II will develop a manufacturing process to support mass production and will initiate the custom design of one or more instruments for specific assays. Offering a suitable detector for a fraction of the cost of current technologies will facilitate the widespread adoption and development of assays that are faster and more accurate than current common practices. Industries in the U.S. will benefit from increased quality and productivity in processes that depend on these assays, and companies that produce the assays will enjoy growth in the demand for their products.