RUI: Gas Phase Studies of Organic Reaction Mechanisms. An Experimental and Ab Initio Study: The Development of Ionic Platforms for Chemistry

RUI：有机反应机理的气相研究。

• 批准号: 9974506
• 负责人: Scott Gronert
• 金额: $ 14万
• 依托单位: San Francisco State University
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 1999
• 资助国家: 美国
• 起止时间: 1999-07-01 至 2003-06-30
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=9974506&HistoricalAwards=false
• 关键词: RUI; Gas; Phase; Studies; Organic

This project uses a combination of experimental and computational approaches to study the mechanisms of gas phase organic reactions. the gas phase work provides information on the intrinsic reactivity of species in the absence of solvation. Comparision with condensed-phase data will give insight into the effects of solvation and ion-pairing on the mechanism. Using a substrate in which one ion undergoes a chemical reaction while another remains intact, mass spectrophotometric data will be obtained for characterization of the reaction product. In this way, gas phase substitution and elimination reactions will be studied.With this Research at Undergraduate Institutions (RUI) Award, the Organic and Macromolecular Chemistry Program supports the research of Scott Gronert of San Francisco State University. Professor Gronert's research explores the outcomes of chemical reactions in the gas phase, in the absence of solvent molecules. In this way, it may be possible to more fully understand the fundamental nature of these reaction and, by comparison with the same reactions carried out in solvent, conclusions may be reached with regard to the role of solvent molecules in mediating chemical reactions.

该项目采用实验和计算相结合的方法来研究气相有机反应的机理。 气相工作提供了在没有溶剂化的情况下物种的固有反应性的信息。 通过与凝聚相数据的比较，可以进一步了解溶剂化和离子配对对机理的影响。 使用其中一个离子经历化学反应而另一个离子保持完整的基质，将获得质谱分光光度数据用于表征反应产物。 通过这种方式，气相取代和消除反应将被研究。有了这个研究在本科院校（RUI）奖，有机和高分子化学计划支持研究的斯科特Gronert的旧金山弗朗西斯科州立大学。 Gronert教授的研究探索了在没有溶剂分子的情况下气相中化学反应的结果。 通过这种方式，可以更充分地理解这些反应的基本性质，并且通过与在溶剂中进行的相同反应进行比较，可以得出关于溶剂分子在介导化学反应中的作用的结论。