Acquisition of a New 400 MHz NMR Spectrometer and Upgrade of an Existing Spectrometer

在化学研究仪器和设施（CRIF）计划的支持下，肯塔基大学化学系将获得一台400 MHz核磁共振光谱仪。该设备将加强在许多领域的研究，包括研究1)阳离子基团13化合物的形成；2)形成单偶联基团13阴离子；3)氧化铝耐腐蚀涂层的前驱体分子；4)在水中的有机构象和功能；5) p堆叠文件夹；6)伪环肽；富勒烯的化学性质；8) DNA动力学；9)蛋白质前酰化化学探针；10)酶的氧化还原催化；11) FeSOD活性位点；12)模型黄素的研究；还有氢键伙伴。核磁共振（NMR）波谱是化学家用来阐明分子结构的最有力的工具。它用于识别未知物质，表征分子内原子的特定排列，并研究溶液中分子之间相互作用的动力学。获得最先进的核磁共振光谱是必不可少的化学家谁正在进行前沿研究。这些核磁共振研究的结果将在聚合物、催化和材料科学等领域特别有用。

With support from the Chemistry Research Instrumentation and Facilities (CRIF) Program, the Department of Chemistry at the University of Kentucky will acquire a 400 MHz NMR Spectrometer. This equipment will enhance research in a number of areas, including studies on 1) the formation of cationic group 13 compounds; 2) formation of uni-ligated group 13 anions; 3) precursor molecules to corrosion resistant coatings of alumina; 4) organic conformation & function in water; 5) p-stacked foldamers; 6) pseudocyclic peptides; 7) the chemistry of fullerenes; 8) DNA dynamics; 9) chemical probes of protein prenylation; 10) redox catalysis in enzymes; 11) active site of FeSOD; 12) studies on model flavins; and 13) hydrogen bonding partners.Nuclear Magnetic Resonance (NMR) spectroscopy is the most powerful tool available to chemists for the elucidation of the structure of molecules. It is used to identify unknown substances, characterize specific arrangements of atoms within molecules, and to study the dynamics of interactions between molecules in solution. Access to state-of-the-art NMR spectrometry is essential to chemists who are carrying out frontier research. Results from these NMR studies will be especially useful in areas such as polymers, catalysis, and in materials science.