Acquisition of a New 400 MHz NMR Spectrometer and Upgrade of an Existing Spectrometer

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With support from the Chemistry Research Instrumentation and Facilities (CRIF) Program, the Department of Chemistry at the University of Kentucky will acquire a 400 MHz NMR Spectrometer. This equipment will enhance research in a number of areas, including studies on 1) the formation of cationic group 13 compounds; 2) formation of uni-ligated group 13 anions; 3) precursor molecules to corrosion resistant coatings of alumina; 4) organic conformation & function in water; 5) p-stacked foldamers; 6) pseudocyclic peptides; 7) the chemistry of fullerenes; 8) DNA dynamics; 9) chemical probes of protein prenylation; 10) redox catalysis in enzymes; 11) active site of FeSOD; 12) studies on model flavins; and 13) hydrogen bonding partners.Nuclear Magnetic Resonance (NMR) spectroscopy is the most powerful tool available to chemists for the elucidation of the structure of molecules. It is used to identify unknown substances, characterize specific arrangements of atoms within molecules, and to study the dynamics of interactions between molecules in solution. Access to state-of-the-art NMR spectrometry is essential to chemists who are carrying out frontier research. Results from these NMR studies will be especially useful in areas such as polymers, catalysis, and in materials science.