CAREER: Synthesis and Molecular Transport Properties of Organic Polymer-Metal Particle Composites and Hollow Polymer Nanocapsules

职业：有机聚合物-金属颗粒复合材料和空心聚合物纳米胶囊的合成和分子传输性能

• 批准号: 9984973
• 负责人: Daniel Feldheim
• 金额: $ 24.8万
• 依托单位: North Carolina State University
• 依托单位国家: 美国
• 项目类别: Continuing Grant
• 财政年份: 2000
• 资助国家: 美国
• 起止时间: 2000-02-15 至 2004-01-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=9984973&HistoricalAwards=false
• 关键词: CAREER; Synthesis; Molecular; Transport; Properties

This Faculty Early Career Development Program award to Dr. Daniel Feldheim of North Carolina State University is supported by the Advanced Materials and Processing Program in the Chemistry Division. The focus of the research will be the preparation of polymer-coated gold colloids and subsequent removal of the gold core resulting in hollow polymer nanocapsules. Polypyrrole and N-methylpyrrole will be synthesized for the preparation of polymer-gold particles. The hollow polymer nanocapsules will be evaluated for uptake, release and entrapment of molecules, and establish structure-function relationships between the polymer capsules and the entrapped molecules. The educational part of the program is to provide cross-disciplinary research experience to undergraduate students with monthly meetings and presentations including invited speakers from industry and academia.Multifunctional polymer capsules will be prepared to encapsulate small molecules for controlled release or activity with potential applications in time-released drug delivery systems. The teaching part of the award will develop an undergraduate research program with support from industry and former NC State chemistry graduates to better prepare the students for careers in chemistry.

这项授予北卡罗来纳州立大学Daniel Feldheim博士的教职早期职业发展计划奖得到了化学部先进材料和加工计划的支持。研究的重点将是制备聚合物包覆的金胶体，然后去除金核，从而形成中空的聚合物纳米胶囊。将合成聚吡咯和N-甲基吡咯，用于制备聚合物金颗粒。中空聚合物纳米胶囊将评估分子的吸收、释放和包埋，并建立聚合物胶囊和包埋分子之间的结构-功能关系。该计划的教育部分是通过每月的会议和演讲为本科生提供跨学科的研究经验，包括来自工业界和学术界的特邀演讲者。多功能聚合物胶囊将被制备成封装小分子以用于控制释放或活性，并在时间释放药物输送系统中潜在的应用。该奖项的教学部分将在工业界和前北卡罗来纳州州立大学化学毕业生的支持下开发一个本科生研究计划，以更好地为学生在化学领域的职业生涯做好准备。