University of Puerto Rico Research Site with Purdue University I/U CRC for Pharmaceutical Processing Research

EEC-0002916 GhalyThe拟议的研究议程强调在分子水平上理解加工对药品关键质量属性的影响，并通过改进工艺监测最大限度地减少验证要求。 代表性的研究项目将包括改进的过程监测技术，药物粉末的混合，近红外光谱在药物测试中的应用，固态特性，配方开发，挤出机/marumerizar技术，压实工艺，验证，溶解和生物利用度的创新分析方法，片剂包衣和分散系统。

EEC-0002916GhalyThe proposed research agenda stresses understanding, at the molecular level, the effects of processing on critical quality attributes of pharmaceutical products and on minimizing validation requirements through improved process monitoring. Representative research projects will include improved process monitoring technology, blending of pharmaceutical powders, application of Near-IR to pharmaceutical testing, solid state properties, formulations development, extruder/marumerizar technology, compaction process, innovative analytical methods for validation, dissolution and bio-availability, tablets coating and disperse systems.