GeneX: An Internet Accessible Gene Expression Database

GeneX：可通过互联网访问的基因表达数据库

• 批准号: 0078307
• 负责人: William Beavis
• 金额: $ 50万
• 依托单位: National Center for Genome Resources
• 依托单位国家: 美国
• 项目类别: Continuing Grant
• 财政年份: 2001
• 资助国家: 美国
• 起止时间: 2001-04-01 至 2004-09-30
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=0078307&HistoricalAwards=false
• 关键词: GeneX; Internet; Accessible; Gene; Expression

Gene expression (GE) data provide snapshots of the cellular biology of living organisms. However, unlike sequence data, GE data only have meaning in an experimental context. Representing that context in a compact, logical way is one of the tasks of this project. Like sequence data, GE data becomes most valuable when they are pooled and become searchable. For this to happen, lab systems must exchange data with higher level databases in a compatible manner. Such compatibility would allow efficient, low-cost sharing of data, in turn encouraging distributed development of objective statistical approaches in evaluating GE data, such as dealing with differences within and between technologies. It would also help to establish baseline levels of GE under many conditions. This project is a pilot study targeted at developing a GE database system that would address such problems in that it 1. Would be freely available as an Open Source project, 2. Could exchange data in a standard format, 3. Would include all the software required to install and run the system locally, and 4. Would be scalable from lab systems to institutional repositories. As a component of the establishment of proof of concept, the project implements a pilot, publicly available installation of contributed GE data.

基因表达（GE）数据提供了活生物体细胞生物学的快照。 然而，与序列数据不同，GE数据仅在实验背景下具有意义。 以紧凑、逻辑的方式表示该上下文是该项目的任务之一。 与序列数据一样，GE数据在汇集并可搜索时变得最有价值。 为此，实验室系统必须以兼容的方式与更高级别的数据库交换数据。 这种兼容性将允许有效、低成本地分享数据，反过来又鼓励在评估通用电气数据时分散地制定客观的统计方法，例如处理技术内部和技术之间的差异。 它还将有助于确定许多情况下的GE基线水平。该项目是一项试点研究，旨在开发一个通用电气数据库系统，以解决这些问题，因为它1。将作为一个开源项目免费提供，2。能够以标准格式交换数据; 3.包括在本地安装和运行系统所需的所有软件; 4.将可从实验室系统扩展到机构存储库。 作为建立概念证明的一个组成部分，该项目实施了一个试点，公开提供的通用电气数据的安装。