GeneX: An Internet Accessible Gene Expression Database

基因表达(GE)数据提供了生命有机体细胞生物学的快照。然而，与序列数据不同，GE数据仅在实验环境中具有意义。以紧凑、合乎逻辑的方式表示该上下文是该项目的任务之一。与序列数据一样，GE数据在汇集在一起并变得可搜索时变得最有价值。要做到这一点，实验室系统必须以兼容的方式与更高级别的数据库交换数据。这种兼容性将允许高效、低成本地共享数据，进而鼓励分散发展客观的统计方法来评估全球环境数据，例如处理技术内部和技术之间的差异。它还将有助于在许多情况下确定通用电气的基准水平。这个项目是一个试验性研究，旨在开发一个GE数据库系统，以解决这样的问题：1.将作为开放源码项目免费提供；2.可以以标准格式交换数据；3.将包括在本地安装和运行该系统所需的所有软件；4.将可从实验室系统扩展到机构储存库。作为建立概念验证的一个组成部分，该项目对公众提供的通用电气数据进行了试点安装。

Gene expression (GE) data provide snapshots of the cellular biology of living organisms. However, unlike sequence data, GE data only have meaning in an experimental context. Representing that context in a compact, logical way is one of the tasks of this project. Like sequence data, GE data becomes most valuable when they are pooled and become searchable. For this to happen, lab systems must exchange data with higher level databases in a compatible manner. Such compatibility would allow efficient, low-cost sharing of data, in turn encouraging distributed development of objective statistical approaches in evaluating GE data, such as dealing with differences within and between technologies. It would also help to establish baseline levels of GE under many conditions. This project is a pilot study targeted at developing a GE database system that would address such problems in that it 1. Would be freely available as an Open Source project, 2. Could exchange data in a standard format, 3. Would include all the software required to install and run the system locally, and 4. Would be scalable from lab systems to institutional repositories. As a component of the establishment of proof of concept, the project implements a pilot, publicly available installation of contributed GE data.