FT-NMR: Hands-On Access In the Undergraduate Curriculum

FT-NMR：本科课程中的实践访问

• 批准号: 0087655
• 负责人: Robert Smart
• 金额: $ 14.44万
• 依托单位: Grand Valley State University
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2001
• 资助国家: 美国
• 起止时间: 2001-01-01 至 2004-12-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=0087655&HistoricalAwards=false
• 关键词: FT; NMR; Hands; Access; Undergraduate

Chemistry (12)The importance of Fourier Transform-Nuclear Magnetic Resonance (FT-NMR) spectroscopy in modern chemistry is reflected in the 1999 American Chemical Society Committee on Professional Training guidelines for the undergraduate organic chemistry curriculum which recommends hands-on training in 1 H and 13 C NMR for undergraduate students. In addition, more advanced pulse sequences such as 2-D NMR have become increasingly vital tools for the modern chemist. In order to incorporate these recommendations, the Department of Chemistry has purchased a 300 MHz instrument capable of teaching the broad range of experiments that comprise modern FT-NMR. We are infusing this technology across our undergraduate curriculum in a series of experiments, adapted from the current literature (research and educational), that is designed to progressively introduce a series of 1-D and 2-D NMR techniques. In doing so, we are adapting the approach recently instituted at Florida State University (CCLI A&I DUE-9972198), adjusting for the size of our student population and tuned to existing strengths in our curriculum. The instrument is being used first by students in their sophomore-level Organic Chemistry sequence to interpret and to obtain 1 H and 13 C spectra, then in a progressive fashion in Qualitative Organic Analysis, Physical Chemistry, Advanced Synthetic Methods, and Undergraduate Research in which more sophisticated techniques and the multi-nuclear nature of FT-NMR are explored.Outcomes include students with extensive hands-on experience in a variety of NMR techniques. Additionally, we are studying the pedagogy of teaching NMR across the curriculum and are in the process of producing a web accessible database of spectral FID's emphasizing 2-D NMR as a problem-solving tool. The database is providing a unique resource to other universities that may wish to implement 2-D NMR spectroscopy into their curriculum but that lack the instrumental capabilities to do so.

化学（12）傅立叶变换-核磁共振（FT-NMR）光谱在现代化学中的重要性反映在1999年美国化学学会专业培训委员会对本科有机化学课程的指导方针中，该指导方针建议对本科生进行1 H和13 C NMR的实践培训。此外，更先进的脉冲序列，如2-D NMR已成为现代化学家越来越重要的工具。为了纳入这些建议，化学系购买了一台300 MHz的仪器，能够教授包括现代FT-NMR在内的广泛实验。我们正在我们的本科课程中注入这种技术，从目前的文献（研究和教育）改编的一系列实验，旨在逐步引入一系列1-D和2-D NMR技术。在这样做的时候，我们正在调整最近在佛罗里达州立大学（CCLI A I DUE-9972198）制定的方法，调整我们的学生人数的大小，并调整到我们的课程现有的优势。该仪器首先被学生用于他们的预科级有机化学序列，以解释和获得1 H和13 C光谱，然后以渐进的方式用于定性有机分析，物理化学，高级合成方法，和本科研究，其中更复杂的技术和FT-NMR的多核性质进行了探索。成果包括学生广泛的手-在各种核磁共振技术的经验。此外，我们正在研究教学NMR在整个课程的教学方法，并在生产光谱FID的强调2-D NMR作为一个解决问题的工具的网络访问数据库的过程中。该数据库为其他大学提供了一个独特的资源，这些大学可能希望将二维NMR光谱学应用到他们的课程中，但缺乏这样做的仪器能力。