Incorporation of High-Field NMR across Chemistry and Biochemistry Curriculums

化学(12)这个项目的目标是通过在化学和生物化学课程中增加实验室经验来加强学生对核磁共振波谱的理解。为了实现这一目标，已经获得了一台300 MHz傅里叶变换核磁共振(FT核磁共振)光谱仪和额外的核磁共振处理软件副本。为了跟上当前的趋势，核磁共振的额外内容正在增加到五门课程或课程序列中：(1)有机化学入门(二年级)；(2)无机/有机合成；(3)生物化学；(4)高级分析化学；(5)本科生研究。为了实现提案所述的目标，核磁共振理论和实践被纳入两个层面。在第一级，所有的化学、生物和生物化学学生都被介绍到一维和二维的核磁共振实验中，这是一种介绍有机化学的顺序。来自文献(化学教育和研究)的新实验正在被改编和实施。在第二阶段，后续课程的化学和生物化学专业的学生正在进行与他们感兴趣的领域相关的额外的核磁共振实验。文献中的核磁共振实验也被改编并实施到这五门课程中。该部门正在开发其他合适的实验，尤其是在生物化学领域。一旦完成，这些实验将通过适当的传播方法提供给其他人。

Chemistry (12)The goal of this project is to enhance student understanding of NMR spectroscopy through increased laboratory experiences in both the chemistry and biochemistry curriculums. A 300 MHz Fourier Transform Nuclear Magnetic Resonance (FT NMR) spectrometer and additional copies of NMR processing software have been obtained to achieve this goal. Additional coverage of NMR, needed to keep pace with current trends, is being added to five courses or course sequences: (1) introductory (sophomore) organic chemistry; (2) inorganic/organic synthesis; (3) biochemistry; (4) advanced analytical chemistry; and (5) undergraduate research.To achieve the stated goals of the proposal, NMR theory and practice is being incorporated at two levels. At the first level, all chemistry, biology, and biochemistry students are being introduced to 1-D and 2-D NMR experiments in the introductory organic chemistry sequence. New experiments from the literature (chemical education and research) are being adapted and implemented. At the second level, chemistry and biochemistry majors in subsequent courses are conducting additional NMR experiments relevant to their areas of interest. NMR experiments from the literature are being adapted and implemented into these five courses as well. Other suitable experiments, most notably in the biochemistry area, are being developed in the Department. Once complete, these experiments will be made available to others through adequate dissemination methods.