Planning for National Ultrahigh Field Nuclear Magnetic Resonance (NMR) Network

国家超高场核磁共振（NMR）网络规划

• 批准号: 2217492
• 负责人: Tatyana Polenova
• 金额: $ 20万
• 依托单位: University of Delaware
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2022
• 资助国家: 美国
• 起止时间: 2022-04-01 至 2025-03-31
• 项目状态: 未结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=2217492&HistoricalAwards=false
• 关键词: Planning; National; Ultrahigh; Field; Nuclear

With support from both the Division of Biological Infrastructure and the Division of Materials Research, an award is made to the University of Delaware to design and develop plans for a national network of ultrahigh field (UHF) nuclear magnetic resonance (NMR) spectrometer facilities. The overall goal of the project will be to create the most powerful NMR network in the world with comprehensive resources and expertise, spanning key areas of NSF interest, that will be accessible to the entire scientific community within the United States. Gains in sensitivity, resolution, and information content are highly nonlinear with magnetic field strength, and ultrahigh fields combined with state-of-the-art NMR probes and pulse sequences will enable fundamental investigations, with atomic resolution, of emergent phenomena not accessible with the current technologies. State-of-the-art UHF NMR instruments will be sited at strategically located public institutions geographically distributed across the US. The NMR network will be made available to researchers across multiple disciplines for advancing the development and use of in vivo, in vitro, in situ, solution, and solid-state NMR spectroscopy to address diverse problems of high fundamental and technological importance. Instruments will be connected through a central cyberinfrastructure hub and integrated with other high-field and UHF NMR instrumentation. The proposed nationwide UHF NMR network will enable experts and non-experts to access both UHF NMR instruments and a diversity of NMR expertise. The intellectual framework established through the proposed network will provide unique training for students in state- of-the-art NMR methods and applications. The outreach program encompassing training in NMR instrumentation and application of NMR methods will be invaluable for the development of the next generation of scientists.Planning the UHF NMR network will set the stage to address the urgent nationwide need for ultrahigh field NMR infrastructure. The planning activities supported by this award will identify the primary scientific, technical and system performance requirements and associated designs and specifications for the UHF NMR network. Through these activities, the researchers will formulate a plan to execute and manage the UHF NMR network, including a project schedule with identified risks and plans to mitigate them, a governance plan and effective project management methods for tracking progress, costs and performance. Outcomes from this effort will include sound baseline cost estimates for implementation and anticipated operations and maintenance costs. The researchers will also develop plans for effective student training and the involvement of a diverse workforce in instrumentation, facility development, and data analysis.This award reflects NSF's statutory mission and has been deemed worthy of support through evaluation using the Foundation's intellectual merit and broader impacts review criteria.

在生物基础设施司和材料研究司的支持下，向特拉华州大学颁发了一个奖项，以设计和制定国家超高频核磁共振光谱仪设施网络的计划。该项目的总体目标将是创建世界上最强大的NMR网络，拥有全面的资源和专业知识，涵盖NSF感兴趣的关键领域，并可供美国整个科学界使用。灵敏度、分辨率和信息含量的提高与磁场强度高度非线性，而磁共振场与最先进的核磁共振探针和脉冲序列相结合，将使人们能够以原子分辨率对当前技术无法获得的紧急现象进行基础研究。 国家的最先进的超高频核磁共振仪器将设在战略位置的公共机构，地理分布在美国各地。NMR网络将提供给跨多个学科的研究人员，以推进体内，体外，原位，溶液和固态NMR光谱的开发和使用，以解决具有高度基础和技术重要性的各种问题。仪器将通过中央网络基础设施中心连接，并与其他高场和UHF NMR仪器集成。 拟议的全国超高频核磁共振网络将使专家和非专家能够使用超高频核磁共振仪器和各种核磁共振专业知识。通过拟议的网络建立的知识框架将为学生提供最先进的NMR方法和应用的独特培训。包括NMR仪器和NMR方法应用培训在内的推广计划对于下一代科学家的发展将是非常宝贵的。规划UHF NMR网络将为解决全国范围内对超高频NMR基础设施的迫切需求奠定基础。该奖项支持的规划活动将确定UHF NMR网络的主要科学，技术和系统性能要求以及相关设计和规格。通过这些活动，研究人员将制定一个计划来执行和管理UHF NMR网络，包括一个项目时间表，其中包括已确定的风险和减轻风险的计划，一个治理计划和有效的项目管理方法，以跟踪进度，成本和性能。 这一努力的成果将包括合理的实施基线费用估计数以及预期的业务和维护费用。研究人员还将制定有效的学生培训计划，并在仪器，设施开发和数据分析的多元化劳动力的参与。这个奖项反映了NSF的法定使命，并已被认为是值得通过使用基金会的智力价值和更广泛的影响审查标准进行评估的支持。