A Workshop: An Exploration of the Challenges to Assemble the Tree of Life (Yale University Peabody Museum of Natural History/July 28-30, 2000)

0089975 CraCraft和Donogue生物的系统发生分组是预测分类和生物信息系统的基础。 根据系统发育关系组织生物学知识及其平行层次结构对科学和社会的许多部分变得越来越重要（即，基因数据库（如GenBank）。 然而，我们对生命树的理解在所有分类学水平上仍然是非常不完整的，因为系统发育假说的典型特征是分类样本不足，并且数据本身在所包括的分类群中的种类，数量和质量方面往往是可变的。 此外，分析方法的适当性和适用性各不相同，因此很难比较系统发育树。 如果我们要在合理的时间范围内建立一个主要生物群体的生命树，就需要解决这些障碍。 同样重要的是要确保系统发育知识对需要它的研究人员、机构和政府机构是可获得的和有用的。这个建议试图汇集大约25-30名对系统发育研究和信息学（系统发育信息学）感兴趣的领先的系统生物学家和非系统生物学家。 讲习班将试图确定为汇编生命树所需的研究，并在合理的时间范围内向全球用户提供这一信息。 研讨会将提出建议，以促进系统研究界的制度变革，加速系统发育的理解，确定将导致大规模增加系统发育信息数据和改进数据分析的研究工作，并具体说明研究、技术进步和基础设施需求，以存储、检索和处理大量系统发育信息，并使其广泛使用。

0089975Cracraft and DonoghuePhylogenetic groupings of organisms are the basis for predictive classifications and biological information systems. Organizing biological knowledge and their parallel hierarchies according to phylogenetic relationships has become increasingly important for many segments of science and society (i.e., genetic databases such as GenBank). Yet, our understanding of the tree of life is still very incomplete at all taxonomic levels because phylogenetic hypotheses are typically characterized by inadequate taxon samples, and the data themselves are often variable across the included taxa with respect to kind, quantity, and quality. In addition, methods of analysis vary in their appropriateness and applicability, thus making comparison of phylogenetic trees difficult. These impediments need to be addressed if we are to have a tree of life for the major groups of organisms within a reasonable time frame. Equally important will be to ensure that phylogenetic knowledge is accessible and useful to researchers, institutions, and the government agencies who need it.This proposal seeks to bring together approximately 25-30 leading systematic biologists and nonsystematists interested in phylogenetic research and informatics (phyloinformatics). The workshop will attempt to identify the research needed to assemble the tree of life and make that information available to the global user community within a reasonable time frame. The workshop will formulate recommendations designed to promote institutional changes within the systematic research community to accelerate phylogenetic understanding, identify research efforts that will result in large-scale increases in phylogenetically informative data and improve data analysis, and specify research, technological advances, and infrastructural needs to store, retrieve, and manipulate large amounts of phylogenetic information and make it widely avail