Acqusition of a New 500 MHz NMR Spectrometer

购买新型 500 MHz NMR 波谱仪

• 批准号: 0091894
• 负责人: Howard Mayne
• 金额: $ 31.53万
• 依托单位: University of New Hampshire
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2001
• 资助国家: 美国
• 起止时间: 2001-02-15 至 2004-01-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=0091894&HistoricalAwards=false
• 关键词: Acqusition; New; 500; MHz; NMR

With this award from the Chemistry Research Instrumentation and Facilities (CRIF) Program, the Department of Chemistry at the University of New Hampshire will acquire a 500 MHz NMR Spectrometer. This equipment will enable researchers to carry out studies on a) characterization of new cycloadducts of C60 with polyacenes and tetrazines; b) characterization and dynamic NMR studies of polyamines and derivatives, including compounds with strong potential as diagnostic imaging agents and anti-HIV agents; c) development of a novel zinc carbenoid chain extension reaction that will facilitate the inclusion of ketomethylene isosteres as part of combinatorial libraries; and d) studies of supramolecular clusters formed from hybrid ligands. Nuclear Magnetic Resonance (NMR) spectroscopy is the most powerful tool available to chemists for the elucidation of the structure of molecules. It is used to identify unknown substances, to characterize specific arrangements of atoms within molecules, and to study the dynamics of interactions between molecules in solution. Access to state-of-the-art NMR spectrometry is essential to chemists who are carrying out frontier research. The results from these NMR studies will have an impact in a number of areas including materials chemistry, biotechnology and nanotechnology.

凭借化学研究仪器和设施（CRIF）计划的这一奖项，新罕布什尔州大学化学系将获得一台500 MHz NMR光谱仪。这一设备将使研究人员能够进行以下研究：a）鉴定C60与多并苯和四嗪的新型环加合物; B）鉴定和动态NMR研究多胺和衍生物，包括作为诊断显像剂和抗艾滋病毒剂的潜力很大的化合物; c）、开发了一种新的锌类卡宾扩链反应，该反应将促进包含酮亚甲基电子等排体作为组合的一部分，图书馆; d）杂化配体形成的超分子簇的研究。 核磁共振（NMR）光谱是化学家用来阐明分子结构的最有力的工具。它用于识别未知物质，表征分子内原子的特定排列，并研究溶液中分子之间相互作用的动力学。 对于进行前沿研究的化学家来说，使用最先进的核磁共振光谱法至关重要。这些核磁共振研究的结果将在许多领域产生影响，包括材料化学，生物技术和纳米技术。