Conference "First International Symposium on Computational Cell Biology" held March 4-6, 2001 in Lenox, MA.

这笔赠款为将于2001年3月4日至6日在马萨诸塞州勒诺克斯举行的首届计算细胞生物学国际研讨会提供部分支持。计算细胞生物学是一个新兴的交叉学科领域，它响应了对计算方法的需求，以分析和组织关于细胞结构和功能的大量实验数据。虽然已经举行了其他会议，重点是生物信息学和分子和结构生物学，但这将是第一次面向细胞生物学中计算建模应用的会议，并将主要针对细胞生物学家。会议的主要焦点将集中在细胞生物学领域，这些领域的建模方法目前正在开发中，或者是计算建模方法成熟的领域。一个关键的目标是将研究细胞机制的量化方面的细胞生物学家与能够提供计算工具的计算机科学家和数学家聚集在一起。这次研讨会是由国家细胞分析和建模资源(NrCAM)组织的，该资源位于康涅狄格大学健康中心的生物医学成像技术中心(CBIT)。组委会由博士生组成。NrCAM和CBIT主任Leslie M.Loew，NrCAM联席主任John Carson和CBIT副教授Vladimir Rodionov，并由CBIT副主任兼NrCAM传播和培训负责人Ann Cowan担任主席。组委会成员认为，将细胞生物学家、数学家和计算机科学家聚集在一起发展一个真正的科学家社区的时机已经成熟，他们的共同目标是开发用于细胞生物学建模和模拟的计算工具。会议的主题将包括一系列的细胞机制，包括细胞骨架和分子马达的调节，膜和蛋白质的运输，钙动力学的调节，信号转导通路和细胞周期控制。在这些领域中的每一个领域，将邀请利用高定量实验方法和/或正在应用数学建模方法的主要研究人员发言。这次会议将是一场密集的混合会议，包括平台会议、海报会议以及小型研讨会和教程。会议的地点是伯克郡山区的一个度假胜地，最多只能有125人参加。这种背景和会议规模将是鼓励这一不同科学家群体之间进行个人互动的理想选择。对于在这个年轻和不断扩大的领域工作的研究生和博士后来说，它也将是一个极好的教育活动。

This grant provides partial support for the First International Symposium on Computational CellBiology to be held March 4-6, 2001 in Lenox, MA. Computational Cell Biology is an emerging interdisciplinary field that responds to the need for computational methods to analyze and organize the abundance of experimental data on the structure and function of the cell. Whereas other meetings have been held that focus on bioinformatics and molecular and structural biology, this will be the first meeting geared to the use of computational modeling applications in cell biology, and will be primarily targeted to cellbiologists. The major focus of the meeting will be on areas of cell biology for which modeling approaches are currently being developed, or that are ripe for computational modeling approaches. A key goal is to bring together cell biologists whose research addresses quantitative aspects of cellular mechanisms with computer scientists and mathematicians who can provide the computational tools. The symposium is being organized by The National Resource for Cell Analysis and Modeling (NRCAM), located in the Center for Biomedical Imaging Technology (CBIT) at the University of Connecticut Health Center. The organizing committee consists ofDrs. Leslie M. Loew, Director of NRCAM and CBIT, John Carson, co-Director of NRCAM and Vladimir Rodionov, associate faculty of CBIT, and is chaired by Ann Cowan, Deputy Director of CBIT and head of dissemination and training for NRCAM. The members of the organizing committee feel that the time is ripe to bring together cell biologists, mathematicians, and computer scientists to develop a true community of scientists sharing the common goal of developing computational tools for cell biological modeling and simulation. Topics at the meetings will encompass a range of cellular mechanisms including regulation of the cytoskeleton and molecular motors, membrane and protein trafficking, regulation of calcium dynamics, signal transduction pathways, and cell cycle control. In each of these areas key researchers who utilize highly quantitative experimental approaches and/or are applying mathematical modeling approaches will be invited to speak. The meeting will be an intensive mix of platform sessions, poster sessions and small workshops and tutorials. The venue for the meeting is a resort in the Berkshire mountains that is limited to a maximum of 125 participants. This setting and meeting size will be ideal for encouraging individual interactions between this diverse group of scientists. It will also serve as an excellent educational activity for graduate andpostdoctoral students working in this young and expanding field.