Synthesis, Reactions, and Applications of Organic "Super" Photoacids
有机“超级”光酸的合成、反应和应用
基本信息
- 批准号:0096941
- 负责人:
- 金额:$ 46万
- 依托单位:
- 依托单位国家:美国
- 项目类别:Continuing Grant
- 财政年份:2001
- 资助国家:美国
- 起止时间:2001-07-01 至 2004-12-31
- 项目状态:已结题
- 来源:
- 关键词:
项目摘要
This research focuses on the synthesis and photochemistry of new super photoacids, including their application to biological and photoresist systems. Proton transfer represents one of the two most fundamental processes in nature, yet techniques for studying the dynamics of this process have relied on relatively inefficient, commercially-available materials. This is in contrast to electron transfer, which has seen an overwhelming synthetic, mechanistic, and dynamic effort. Although many similarities exist between the two, including solvent-dependent kinetics rationalized through Marcus theory, photoexcitation creates electrochemical driving forces, which are readily rationalized by an analysis of oxidation/reduction potentials. The occurrence of proton transfer in the excited state presents unique opportunities to study the chemistry and dynamics of this fundamental process using ultrafast time-resolved techniques, if the electronic structure of the excited state can be understood. This project involves the design and synthesis of new substrates that test concepts of structure, driving force, and entropy and that allow correlations to be made with theory. This approach uses a knowledge of the electronic structure of excited-states of acids to design molecules which exhibit enhanced excited-state acidity. Some of these, which are termed "super" photoacids, are the strongest reversible photoacids known. Synthetic methodologies will be developed to achieve molecules whose photoacidity can be tailored thereby providing new methods for studies of proton transfer reactions and novel polymerization catalysts. The research introduces graduate and postdoctoral students to new concepts in acid-base chemistry and kinetics, and to the methodologies to examine these transient effects.With this award, the Organic and Macromolecular Chemistry Program supports the research of Professor Laren Tolbert of the School of Chemistry and Biochemistry at Georgia Institute of Technology. Professor Tolbert will focus his research efforts on the synthesis and excited state chemistry of molecules, called photoacids, whose acid-base properties change on optical excitation. These molecules, which can exhibit immense, but transient, changes in acid-base properties, provide new methods to study acid-base chemistry, and novel approaches to photoactivated, polymerization catalysts. Professor Tolbert is expanding his research efforts through collaborations with Professors Robert Dickson in his Department, Juergen Ruehe of Frieburg University and Menachim Gutman at the University of Tel Aviv. Through Professor Tolbert's research, graduate and postdoctoral students will be exposed to new concepts in acid-base chemistry, and the methodology to examine these transient effects.
本研究的重点是新型超级光酸的合成和光化学,包括它们在生物和光致抗蚀剂体系中的应用。质子转移是自然界中两个最基本的过程之一,然而研究这一过程动力学的技术依赖于相对低效的商业材料。这与电子转移形成鲜明对比,电子转移已经经历了压倒性的合成、机械和动态的努力。虽然两者之间存在许多相似之处,包括通过马库斯理论合理化的溶剂依赖性动力学,光激发产生电化学驱动力,这是很容易合理化的氧化/还原电位的分析。在激发态质子转移的发生提供了独特的机会,研究化学和动力学的这个基本过程,使用超快时间分辨技术,如果激发态的电子结构可以理解。该项目涉及新基板的设计和合成,以测试结构,驱动力和熵的概念,并允许与理论的相关性。这种方法利用酸的激发态的电子结构的知识来设计表现出增强的激发态酸性的分子。其中一些被称为“超级”光酸,是已知的最强的可逆光酸。将开发合成方法以获得其光酸性可以定制的分子,从而为质子转移反应和新型聚合催化剂的研究提供新的方法。该研究向研究生和博士后学生介绍了酸碱化学和动力学的新概念,以及检查这些瞬态效应的方法。有了这个奖项,有机和高分子化学项目支持格鲁吉亚理工学院化学和生物化学学院的拉伦·托尔伯特教授的研究。Tolbert教授将把他的研究重点放在分子的合成和激发态化学上,称为光酸,其酸碱性质在光激发下发生变化。这些分子,可以表现出巨大的,但短暂的,酸碱性质的变化,提供了新的方法来研究酸碱化学,和新的方法,光活化,聚合催化剂。托尔伯特教授正在扩大他的研究工作,通过与教授罗伯特迪克森在他的部门,于尔根Ruehe弗里堡大学和Menachim古特曼在特拉维夫大学的合作。通过托尔伯特教授的研究,研究生和博士后学生将接触到酸碱化学的新概念,以及研究这些瞬态效应的方法。
项目成果
期刊论文数量(0)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
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Laren Tolbert其他文献
Laren Tolbert的其他文献
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{{ truncateString('Laren Tolbert', 18)}}的其他基金
International Collaboration in Chemistry: Directed synthesis of graphene nanoribbons
国际化学合作:石墨烯纳米带的定向合成
- 批准号:
0822697 - 财政年份:2008
- 资助金额:
$ 46万 - 项目类别:
Standard Grant
Excited-State Proton Transfer in Chemistry and Biology
化学和生物学中的激发态质子转移
- 批准号:
0809179 - 财政年份:2008
- 资助金额:
$ 46万 - 项目类别:
Continuing Grant
Toward a Quantitative Model for Excited-State Proton Transfer: From "Super" Photoacids to the Green Fluorescent Protein
激发态质子转移的定量模型:从“超级”光酸到绿色荧光蛋白
- 批准号:
0456892 - 财政年份:2005
- 资助金额:
$ 46万 - 项目类别:
Continuing Grant
Discovery Corps Senior Fellowship: Professor in Residence at Clark Atlanta University
探索队高级研究员:克拉克亚特兰大大学常驻教授
- 批准号:
0513361 - 财政年份:2005
- 资助金额:
$ 46万 - 项目类别:
Standard Grant
Minority Ph.D.'s in Chemistry: What Are We Doing Wrong?
少数族裔化学博士:我们做错了什么?
- 批准号:
9978844 - 财政年份:1999
- 资助金额:
$ 46万 - 项目类别:
Standard Grant
Synthesis and Reactions of Transient Acids
瞬态酸的合成与反应
- 批准号:
9727157 - 财政年份:1998
- 资助金额:
$ 46万 - 项目类别:
Continuing Grant
U.S.-Japan Workshop: New Aspects of Photoresponsive Materials
美日研讨会:光响应材料的新面貌
- 批准号:
9602876 - 财政年份:1996
- 资助金额:
$ 46万 - 项目类别:
Standard Grant
Acid-Base Properties of Photoexcited Molecules
光激发分子的酸碱性质
- 批准号:
9111768 - 财政年份:1991
- 资助金额:
$ 46万 - 项目类别:
Continuing Grant
Charge Distribution in Photoexcited Molecules
光激发分子中的电荷分布
- 批准号:
8805577 - 财政年份:1988
- 资助金额:
$ 46万 - 项目类别:
Continuing Grant
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