CONFERENCE: Junior Investigator Participation in FASEB Conference on Biological Methylation to be held from July 21-26, 2001, at the Vermont Academy in Saxtons River, Vermont

这项赠款为年轻的研究人员提供支持，以参加2001年7月21日至26日在萨克斯顿河，佛蒙特州举行的2001年美国实验生物学学会联合会（FASEB）关于生物甲基化的夏季研究会议。这次会议是1993年开始在FASEB主持下举行的一系列两年期会议中的第五次会议。 这些会议的组织是为了响应会议的需要，重点是S-腺苷甲硫氨酸（NAMET），大多数生物甲基化反应的甲基供体，以及细胞中各种NAMET依赖性转甲基化反应。2001年会议的大约一半会议将集中讨论DNA甲基化，因为DNA甲基化已被证明在基因表达、印记和肿瘤发生的调节中发挥重要作用。 会议将讨论的其他主题包括CIMMet和人类健康，参与衰老和基因表达的各种蛋白质甲基化反应，以及在化疗中重要的小分子甲基化反应。 本次会议为对ADMet甲基化和ADMet代谢的各个方面感兴趣的科学家提供了一个独特的机会进行互动，这在任何其他会议上都没有实现。因此，本次会议历来是富有成效的合作的起点。 与会者的专业知识差异很大，从合成化学到分子生物学，再到生理学和医学。

This grant provides support for young investigators to attend the 2001 Federation of American Societies for Experimental Biology (FASEB) Summer Research Conference on Biological Methylation to be held on July 21-26, 2001, in Saxton River, VT. This conference is the fifth in a series of biennial conferences that began in 1993, under the auspices of the FASEB. These conferences were organized in response to the need for a conference with a focus on S-adenosylmethionine (AdoMet), the methyl donor for most biological methylation reactions, and the various AdoMet-dependent transmethylation reactions in cells. Approximately half of the 2001 meeting's sessions will be focused on the methylation of DNA, as DNA methylation has been shown to play important roles in the regulation of gene expression, imprinting and tumorigenesis. Other topics to be discussed at the meeting include the AdoMet and human health, various protein methylation reactions involved in aging and gene expression, and small molecule methylation reactions important in chemotherapy. This Conference provides a unique opportunity for scientists interested in various aspects of AdoMet methylation and AdoMet metabolism to interact, which is not achieved at any other conference. Consequently, this meeting has traditionally provided the starting point for productive collaborations. The expertise of attendees varies widely, ranging from synthetic chemistry to molecular biology to physiology and medicine.