SGER: Nanostructured Drug Delivery Systems
SGER: Nanostructured Drug Delivery Systems
批准号:
0118705
负责人:
Jackie Ying
金额:
$10.0万
依托单位国家:
美国
项目类别:
Standard Grant
财政年份:
2001
资助国家:
美国
项目状态:
已结题
起止时间:
2001-07-01 至 2002-12-31
中文摘要
CTS-0118705Jackie Ying,MIT提出了一种智能药物输送系统的设计可行性。它的设计将基于纳米组件,这些组件被组织成质量、表面和化学分布,这将优化输送,同时适应其身体环境的性质。这就是用合成载体纳米装置传递胰岛素,这通常会保护胰岛素负荷不受胃肠道酸性的影响,并且还具有自适应的化学分布,当载体到达流动的一部分时,将释放所包含的胰岛素,显示出预定的环境化学性质。
英文摘要
AbstractCTS-0118705Jackie Ying, MITIt is proposed to investigate the design feasibility of an intelligent drug delivery system. Its design would be based on nanometer components organized into mass, surface and chemistry distributions which will optimize the delivery, while adapting to the nature of its body environment. Such would be the delivery of insulin with a synthetic carrier nanodevice, which would typically protect the insulin load from gastrointestinal acidity, and also have an adaptive chemical distribution which will release the contained insulin when the carrier would reach a part of the flow showing predetermined ambient chemical properties.
期刊论文(0)
专著(0)
科研奖励(0)
会议论文
Engineering Foundation Conference on "Processing and Catalytic/Chemical Properties of Nanostructured Materials" to be held in Maui, Hawaii from January 16 - 21, 2000
-
批准号:0001335
-
项目类别:Standard Grant
-
资助金额:$1.24万
-
财政年份:2000
-
负责人:Jackie Ying
-
依托单位:
SGER: Modified Sol-Gel Processing of Nanostructured Multifunctional Active Coatings
-
批准号:9731396
-
项目类别:Standard Grant
-
资助金额:$5.0万
-
财政年份:1997
-
负责人:Jackie Ying
-
依托单位:
REG: X-Ray Powder Diffractometer for Characterization of Ultrafine Materials and Novel Structures
-
批准号:9411901
-
项目类别:Standard Grant
-
资助金额:$5.5万
-
财政年份:1994
-
负责人:Jackie Ying
-
依托单位:
NSF Young Investigator: Structural Tailoring of Nanoscale Materials for Catalysis and Ceramics
-
批准号:9257223
-
项目类别:Continuing grant
-
资助金额:$0.0万
-
财政年份:1992
-
负责人:Jackie Ying
-
依托单位:
NSF-NATO Postdoctoral Fellow
-
批准号:9154482
-
项目类别:Fellowship Award
-
资助金额:$3.65万
-
财政年份:1991
-
负责人:Jackie Ying
-
依托单位:
海外基金