ITR/SY+PE+IM+AP Collaborative Research: Computer-Linked Auto-Fabricated Models for Education in Molecular Biology

ITR/SY PE IM AP 合作研究：用于分子生物学教育的计算机连接自动制作模型

• 批准号: 0121282
• 负责人: Arthur Olson
• 金额: $ 43.09万
• 依托单位: The Scripps Research Institute
• 依托单位国家: 美国
• 项目类别: Continuing Grant
• 财政年份: 2001
• 资助国家: 美国
• 起止时间: 2001-10-01 至 2005-09-30
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=0121282&HistoricalAwards=false
• 关键词: ITR; SY+PE+IM+AP; Collaborative; Research; Computer

This is a research project in the design and implementation of novel Human Computer Interfaces for educational use in structural molecular biology. This project will explore, define, and assess the role of computer-generated physical models in teaching scientific content and concepts. The purpose is to enhance the understanding and communication of the complex world of life's molecular machinery to a broad community. Using structural data on biological molecules and their complexes, the participants will prototype novel physical models via automated design and fabrication technologies and develop replication processes for broader distribution. The models will be used directly for enhance visualization and as input/output devices that interactively integrate with commutation and computer graphics for information retrieval, manipulation, and simulation.This project will provide new, tangible modes of interacting with, and understanding of, both the fundamental concepts and the complex data that are coming from the rapid advances in genomics, proteomics, and other areas of structural molecular biology. It will enable a broad range of students to learn, query, and explore in a field of growing scientific and social importance - the molecular basis of life. Physical models will give both haptic and visual support of the importance of shape in biological function. Use of physical models as tangible computer interfaces will revolutionize how students explore and understand biomolecular structure, interaction, and function.

这是一个研究项目，在设计和实现新颖的人机界面，用于结构分子生物学的教育用途。 这个项目将探索，定义和评估计算机生成的物理模型在教学科学内容和概念中的作用。 其目的是加强理解和沟通的复杂世界的生命的分子机制，以一个广泛的社区。 利用生物分子及其复合物的结构数据，参与者将通过自动化设计和制造技术建立新型物理模型的原型，并开发复制过程以实现更广泛的分布。 这些模型将直接用于增强可视化，并作为输入/输出设备，与通信和计算机图形交互式地集成，用于信息检索、操作和模拟。该项目将提供新的、有形的模式，与来自基因组学、蛋白质组学、和其他结构分子生物学领域。 它将使广泛的学生学习，查询，并在日益增长的科学和社会重要性的领域探索-生命的分子基础。 物理模型将为形状在生物功能中的重要性提供触觉和视觉支持。 使用物理模型作为有形的计算机接口将彻底改变学生如何探索和理解生物分子的结构，相互作用和功能。