FSML: Molecular Biology Core Facility for Grice Marine Laboratory

FSML：格赖斯海洋实验室分子生物学核心设施

• 批准号: 0122336
• 负责人: Craig Plante
• 金额: $ 10.16万
• 依托单位: College of Charleston
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2001
• 资助国家: 美国
• 起止时间: 2001-11-01 至 2005-10-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=0122336&HistoricalAwards=false
• 关键词: FSML; Molecular; Biology; Core; Facility

A grant has been awarded to Drs. Craig Plante and Louis Burnett at the College of Charleston to establish a core facility for molecular/genomic research at the Grice Marine Laboratory. The Grice Marine Laboratory (GML) serves as the primary facility in support of the undergraduate and the graduate programs in marine biology of the College of Charleston and the University of Charleston, SC. As the College of Charleston student population has rapidly grown to over 9500, the size of the Biology Department has increased from 20 to 32 faculty since 1993. Reflecting the department's goal to offer more opportunities for research to its undergraduates, research success has been emphasized in these recent hirings to a greater extent than in the past. Consequently, the scope and scale of research has expanded over the past decade, requiring a higher level of methodological sophistication. These shifts have necessitated the use of more contemporary protocols, including modern molecular approaches. This modernization will allow the GML to better fulfill its mission to support undergraduate and graduate student education; acquire and disseminate knowledge about marine organisms, processes, and environmental issues; and encourage collaborative interdisciplinary marine research among academic and other marine research facilities. Acquisition of an automated DNA sequencer, image analysis system, thermal cyclers, PCR work station and additional versatile equipment will make available new and exciting capabilities for scientists and students at the College of Charleston and beyond. Projects of the nine resident GML faculty and their students include study of microbial diversity in marine sediments, molecular mechanisms of immune responses in fish and shrimp, patterns of paternity in sea turtles, antibiotic-resistant pathogenic bacteria in aquaculture, and phylogenetic studies of marine invertebrates and fish.This shared-use facility will benefit faculty and student research, undergraduate and graduate students, and a broader group of visiting scientists and summer interns at the GML. Furthermore, these resources will be available to our partners in the larger community at the Fort Johnson research complex, which includes scientists at the laboratories of the South Carolina Marine Resources Research Institute, the Marine Biomedical and Environmental Studies Program of the Medical University of South Carolina, and the Charleston laboratories of the National Ocean Service and the National Institute of Standards and Technology.

已向博士授予补助金。查尔斯顿学院的克雷格·普兰特 (Craig Plante) 和路易斯·伯内特 (Louis Burnett) 将在格赖斯海洋实验室建立分子/基因组研究核心设施。 格莱斯海洋实验室 (GML) 是支持查尔斯顿学院和南卡罗来纳州查尔斯顿大学海洋生物学本科生和研究生课程的主要设施。 随着查尔斯顿学院的学生人数迅速增长到超过 9500 人，自 1993 年以来，生物系的教员规模从 20 人增加到 32 人。最近的招聘比过去更加强调了研究的成功，这反映了该系为本科生提供更多研究机会的目标。 因此，在过去十年中，研究的范围和规模不断扩大，对方法论的复杂程度提出了更高的要求。 这些转变需要使用更现代的方案，包括现代分子方法。 此次现代化改造将使 GML 更好地履行其支持本科生和研究生教育的使命；获取并传播有关海洋生物、过程和环境问题的知识；鼓励学术机构和其他海洋研究机构之间开展跨学科海洋研究合作。 购买自动 DNA 测序仪、图像分析系统、热循环仪、PCR 工作站和其他多功能设备将为查尔斯顿学院及其他地区的科学家和学生提供令人兴奋的新功能。 GML 九名常驻教师及其学生的项目包括海洋沉积物中微生物多样性的研究、鱼和虾免疫反应的分子机制、海龟的亲子关系模式、水产养殖中的抗生素抗性致病菌以及海洋无脊椎动物和鱼类的系统发育研究。这个共享设施将有利于教师和学生的研究、本科生研究 和研究生，以及 GML 的更广泛的访问科学家和暑期实习生群体。 此外，这些资源将提供给约翰逊堡研究中心更大社区的合作伙伴，其中包括南卡罗来纳州海洋资源研究所实验室、南卡罗来纳医科大学海洋生物医学和环境研究项目以及国家海洋局查尔斯顿实验室和国家标准与技术研究所的科学家。