REU Site: Cellular and Molecular Biology of Stress (CMBS): Exploring the Complexities of Adaptation and Resilience

位于威斯康星州麦迪逊的威斯康星大学麦迪逊分校获得REU Site奖，将在2024-2026年夏季期间支持10名学生进行为期10周的培训。预计共有30名学生将在该方案中接受培训，这些学生主要来自研究机会有限的学校和/或代表性不足的群体。这一研究经验将为学生在研究生院进一步学习做好准备，并使他们在未来的职业生涯中为细胞和分子生物学领域做出重大贡献。学生将学习研究是如何进行的，许多人将在科学会议上展示他们的工作成果。对该计划的评估将通过一个在线工具进行。项目结束后，将对学生进行跟踪，以确定他们的职业道路。REU学生将研究环境应激源如何不断塑造所有生命形式的适应策略，包括生物应激源(源于病原体等活的有机体)和非生物应激源(来自非生物因素，如养分的可用性)。通过积极参与原创研究，学生们将研究细胞如何检测压力，传递和放大压力信号，并改变细胞生理以适应压力。该计划包括与八个生物科学系(细菌学、生物化学、生物分子化学、昆虫学、森林和野生动物生态学、遗传学、医学遗传学和植物病理学)的研究小组合作的各种项目。学生将参加队列会议，帮助他们驾驭研究环境，发展科学交流技能，与生物科学教师和研究生互动，并属于支持性学习社区，以便他们能够从经验中获得最大收获。学生将完成NSF负责任的研究行为培训模块，并在队列会议上继续学习研究伦理。学生应通过NSF ETAP门户网站申请。申请由PI、共同PI和教师导师进行整体审查。该奖项反映了NSF的法定使命，并通过使用基金会的智力优势和更广泛的影响审查标准进行评估，认为值得支持。

This REU Site award to the University of Wisconsin-Madison, located in Madison, WI, will support the training of 10 students for 10 weeks during the summers of 2024-2026. It is anticipated that a total of 30 students, primarily from schools with limited research opportunities and/or from under-represented groups, will be trained in the program. This research experience will prepare students for further studies in graduate school and equip them to make significant contributions to the fields of cellular and molecular biology in their future careers. Students will learn how research is conducted, and many will present the results of their work at scientific conferences. Assessment of the program will be done through an online tool. Students will be tracked after the program to determine their career paths. REU students will investigate how environmental stressors, including both biotic stressors (originating from living organisms such as pathogens) and abiotic stressors (arising from non-living factors such as nutrient availability), constantly shape the adaptive strategies of all life forms. By actively participating in original research, students will examine how cells detect stresses, transfer and amplify stress signals, and alter cell physiology to adapt to stresses. The program includes diverse projects with research groups from eight bioscience departments (Bacteriology, Biochemistry, Biomolecular Chemistry, Entomology, Forest and Wildlife Ecology, Genetics, Medical Genetics, and Plant Pathology). Students will participate in cohort meetings to help them navigate the research environment, develop science communication skills, interact with bioscience faculty and graduate students, and belong to a supportive learning community so they can get the most from their experience. Students will complete the NSF Responsible Conduct of Research training module and continue learning about research ethics in the cohort meetings. Students should apply through the NSF ETAP portal. Applications are reviewed holistically by the PI, co-PI, and faculty mentor.This award reflects NSF's statutory mission and has been deemed worthy of support through evaluation using the Foundation's intellectual merit and broader impacts review criteria.