Laboratory Course Integrating Synthetic and Biomacromolecules

我们最近开发的本科实验课程旨在提供合成和生物大分子的平衡和综合处理，同时为学生提供合成和分析的基本实践经验。本课程与高分子与材料科学的本科课程相关。此外，这样的实验练习在有机化学或物理化学实验课程中也有价值，在这些课程中，基本化学概念的整合可以用本质上有趣的材料来演示：大分子。本课程的教学方法是传达大分子概念，即大分子的科学和工程可以被呈现为一套一般原理和基本原理，而不管其来源如何。我们通过创建一套新的多组分实验室实验来实现这些目标，每个实验都有双重目的：(1)介绍一个特定的大分子概念，(2)介绍一种或多种特定的实验室技术。这些实验室中的每一个都将围绕合成和生物合成途径衍生的大分子进行开发。新课程的一个特别之处在于将大分子分子建模作为本科生的实验练习，从而为学生提供了一个进行实验的途径，即使他们发现自己无法使用传统的实验室设施。如果教师希望采用我们的课程，我们已经创建了一个实验手册教科书，包括介绍材料，详细的实验程序，以及作为一套全面附录的辅助参考材料。通过我们的实验课程，为本科生在大分子科学与工程方面的工业实践、研究生教育和研究生研究奠定了坚实的基础。

Engineering - Materials Science (57)Our recently developed undergraduate laboratory course has been designed to provide a balanced and integrated treatment of synthetic and biomacromolecules, while providing students with essential hands-on experience in their synthesis and analysis. Our course has relevance for undergraduate programs in polymer and materials science. In addition, such laboratory exercises also have value in either organic or physical chemistry lab courses, in which the integration of fundamental chemical concepts can be demonstrated using intrinsically interesting materials: macromolecules. Our pedagogical approach for the course is to convey the macromolecular concept, that the science and engineering of macromolecules can be presented as a set of general principles and fundamentals, regardless of source. We have achieved these objectives by creating a suite of new multicomponent laboratory experiments, each with a dual purpose: (1) introduce a particular macromolecular concept, and (2) introduce one or more particular laboratory techniques. Each of these laboratories will be developed around macromolecules derived from both synthetic and biosynthetic pathways. A special feature of the new course has been molecular modeling of macromolecules as an undergraduate laboratory exercise, thus providing students with an avenue for conducting experiments even if they find themselves without access to traditional laboratory facilities. If faculty wish to adopt our course we have created a laboratory manual textbook, complete with introductory material, detailed experimental procedures, and supporting reference materials as a comprehensive set of appendices. Through our laboratory course, undergraduates have built firm foundations for industrial practice, graduate education, and graduate research in macromolecular science and engineering.