Acquisition of a Pulsed Fourier Transform Electron Paramagnetic Resonance Spectrometer

脉冲傅里叶变换电子顺磁共振波谱仪的采集

• 批准号: 0131048
• 负责人: Michael Wasielewski
• 金额: $ 32.53万
• 依托单位: Northwestern University
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2002
• 资助国家: 美国
• 起止时间: 2002-02-01 至 2005-01-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=0131048&HistoricalAwards=false
• 关键词: Acquisition; Pulsed; Fourier; Transform; Electron

With this award from the Chemistry Research Instrumentation and Facilities (CRIF) Program, the Department of Chemistry at Northwestern University will acquire a Pulsed Fourier Transform Electron Paramagnetic Resonance (EPR) Spectrometer. The new instrument will support research in the following areas: a) mapping electronic coupling within photogenerated radical ion pairs at fixed distances using time-resolved EPR spectroscopy (Wasielewski); b) direct observation of guanine cation radical in duplex DNA (Lewis); c) time-resolved applications in energy conversion chemistry: finding and identifying electron traps at photo-active interfaces (Hupp); d) time-resolved EPR of electron transfer within protein complexes (Hoffman); e) EPR studies on cobalt (II)-substituted zinc-binding domains (Godwin); and f) EPR studies of monoamine oxidase (Silverman). An electron paramagnetic resonance (EPR) spectrometer is an instrument used to obtain information about the molecular and electronic structure of molecules. It may also be used to obtain information about the lifetimes of free radicals which are often essential for the initiation of tumor growth and/or a variety of chemical reactions. These studies will have an impact in a number of areas, in particular the chemistry of photofunctional materials and biophysical chemistry.

根据化学研究仪器和设施（CRIF）项目的这份合同，西北大学化学系将获得一台脉冲傅立叶变换电子顺磁共振（EPR）光谱仪。新仪器将支持以下领域的研究：a)使用时间分辨EPR光谱（Wasielewski）在固定距离上绘制光生自由基离子对内的电子耦合图；b)直接观察双链DNA中的鸟嘌呤阳离子自由基（Lewis）；c)能量转换化学中的时间分辨应用：发现和识别光活性界面上的电子陷阱（Hupp）；d)蛋白质复合物内电子转移的时间分辨EPR (Hoffman)；e)钴（II）取代锌结合结构域的EPR研究（Godwin）；f)单胺氧化酶的EPR研究（Silverman）。电子顺磁共振（EPR）谱仪是一种用于获取分子和分子电子结构信息的仪器。它也可用于获得自由基寿命的信息，自由基对于肿瘤生长和/或各种化学反应的开始通常是必不可少的。这些研究将对许多领域产生影响，特别是光功能材料的化学和生物物理化学。