Analytical Spectroscopy Methods for Colloids and Colloid-derived Materials

犹他州大学的Joel Harris教授由分析和表面化学项目资助，研究用于胶体和胶体衍生材料（例如二氧化硅）研究的单分子荧光成像和光学捕获技术。 单分子荧光成像光谱将用于确定染料标记的分布，计数反应性表面位点，并确定颗粒体积和面积。 光学捕获将提供长的停留时间以观察拉曼散射并确定单个颗粒的化学组成和表面反应的动力学。 各种各样的化学材料和工业过程都依赖于精细分散的固体材料在液体中的分散，探测这些颗粒的化学性质是化学分析的一个挑战。 单分子光谱学和光学捕获的结合正在被其他人使用，特别是在生物化学中，但将这些用于胶体颗粒的建议是独一无二的。

Professor Joel Harris of the University of Utah is funded by the Analytical and Surface Chemistry Program to study single molecule fluorescence imaging and optical trapping techniques for the study of colloids and colloid-derived materials (e.g. silica). Single molecule fluorescence imaging spectroscopy will be used to determine distributions of dye labels, to count reactive surface sites, and to determine particle volume and areas. Optical trapping will provide long residence times to observe Raman scattering and determine chemical composition of individual particles and kinetics of surface reactions. A wide variety of chemical materials and industrial processes depend on the dispersion of finely divided solid materials in liquids, and probing the chemistry of these particles is a challenge for chemical analysis. The combination of single molecule spectroscopy and optical trapping is being used by others, especially in biological chemistry, but the proposal to use these on colloidal particles is unique.